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Details

Stereochemistry ACHIRAL
Molecular Formula C31H24F2N4O3
Molecular Weight 538.5441
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of BMS-929075

SMILES

CNC(=O)C1=C(OC2=C1C(F)=C(C=C2)C3=CC(=CC=C3C)C(=O)NC4(CC4)C5=NC=CC=N5)C6=CC=C(F)C=C6

InChI

InChIKey=LZAUGCMVNLZVJV-UHFFFAOYSA-N
InChI=1S/C31H24F2N4O3/c1-17-4-5-19(28(38)37-31(12-13-31)30-35-14-3-15-36-30)16-22(17)21-10-11-23-24(26(21)33)25(29(39)34-2)27(40-23)18-6-8-20(32)9-7-18/h3-11,14-16H,12-13H2,1-2H3,(H,34,39)(H,37,38)

HIDE SMILES / InChI
Bristol-Myers Squibb developed BMS-929075 as a selective, orally bioavailable hepatitis C virus (HCV) NS5B polymerase inhibitor for the treatment of chronic HCV infection. BMS-929075 was involved in phase I clinical trials for hepatitis C virus (HCV) infected patients; however, the company withdrew a study prior to enrolment.

Approval Year

PubMed

PubMed

TitleDatePubMed
Discovery of a Hepatitis C Virus NS5B Replicase Palm Site Allosteric Inhibitor (BMS-929075) Advanced to Phase 1 Clinical Studies.
2017 May 25

Sample Use Guides

Oral Suspension, ≤ 25 mg, Once daily, 3 days; Oral Suspension, ≤ 100 mg, Once daily, 3 days; Oral Suspension, ≤ 400 mg, Once daily, 3 days
Route of Administration: Oral
Name Type Language
BMS-929075
Common Name English
4-FLUORO-2-(4-FLUOROPHENYL)-N-METHYL-5-(2-METHYL-5-((1-PYRIMIDIN-2-YLCYCLOPROPYL)CARBAMOYL)PHENYL)BENZOFURAN-3-CARBOXAMIDE
Systematic Name English
3-BENZOFURANCARBOXAMIDE, 4-FLUORO-2-(4-FLUOROPHENYL)-N-METHYL-5-(2-METHYL-5-(((1-(2-PYRIMIDINYL)CYCLOPROPYL)AMINO)CARBONYL)PHENYL)-
Systematic Name English
Code System Code Type Description
PUBCHEM
59275404
Created by admin on Sat Dec 16 11:39:44 GMT 2023 , Edited by admin on Sat Dec 16 11:39:44 GMT 2023
PRIMARY
DRUG BANK
DB14950
Created by admin on Sat Dec 16 11:39:44 GMT 2023 , Edited by admin on Sat Dec 16 11:39:44 GMT 2023
PRIMARY
FDA UNII
8S38482CST
Created by admin on Sat Dec 16 11:39:44 GMT 2023 , Edited by admin on Sat Dec 16 11:39:44 GMT 2023
PRIMARY
CAS
1217338-97-0
Created by admin on Sat Dec 16 11:39:44 GMT 2023 , Edited by admin on Sat Dec 16 11:39:44 GMT 2023
PRIMARY