Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C12H17NO3 |
| Molecular Weight | 223.2683 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(CNC1CCC1)C2=CC=C(O)C(O)=C2
InChI
InChIKey=OVTZNVCECJYMDW-UHFFFAOYSA-N
InChI=1S/C12H17NO3/c14-10-5-4-8(6-11(10)15)12(16)7-13-9-2-1-3-9/h4-6,9,12-16H,1-3,7H2
Norbudrine (KWD2109) is a sympathomimetic drug. It is an active bronchospasmolytic agent. KWD2109 shows an in vitro bronchospasmolytic acitivity which is about 14 times better than that of KWD2025. In the in vivo tests or guinea pig bronchospasmolytic activity KWD2109 has an effect which is about 3 times that of KWD2025 after intraperitoneal and oral administration
Approval Year
Sample Use Guides
The compound Norbudrine (KWD2109) and KWD2025 have been compared in preventing bronchospasm induced by histamine aerosol in guinea pigs.
The drug was injected intraperitoneally 15 minutes or administered orally 30 minutes before histamine treatment. To study the duration of the effect, 2 mg/kg was administered orally to intact guinea pigs at different time intervals before the histamine treatment.
Route of Administration:
Other
| Name | Type | Language | ||
|---|---|---|---|---|
|
Official Name | English | ||
|
Code | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Code | English | ||
|
Systematic Name | English | ||
|
Code | English | ||
|
Systematic Name | English | ||
|
Common Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
|
NCI_THESAURUS |
C48149
Created by
admin on Fri Dec 15 15:29:25 GMT 2023 , Edited by admin on Fri Dec 15 15:29:25 GMT 2023
|
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
SUB09355MIG
Created by
admin on Fri Dec 15 15:29:25 GMT 2023 , Edited by admin on Fri Dec 15 15:29:25 GMT 2023
|
PRIMARY | |||
|
2300
Created by
admin on Fri Dec 15 15:29:25 GMT 2023 , Edited by admin on Fri Dec 15 15:29:25 GMT 2023
|
PRIMARY | |||
|
166575
Created by
admin on Fri Dec 15 15:29:25 GMT 2023 , Edited by admin on Fri Dec 15 15:29:25 GMT 2023
|
PRIMARY | |||
|
15686-81-4
Created by
admin on Fri Dec 15 15:29:25 GMT 2023 , Edited by admin on Fri Dec 15 15:29:25 GMT 2023
|
SUPERSEDED | |||
|
127560-12-7
Created by
admin on Fri Dec 15 15:29:25 GMT 2023 , Edited by admin on Fri Dec 15 15:29:25 GMT 2023
|
PRIMARY | |||
|
8P6T83567P
Created by
admin on Fri Dec 15 15:29:25 GMT 2023 , Edited by admin on Fri Dec 15 15:29:25 GMT 2023
|
PRIMARY | |||
|
DTXSID50864619
Created by
admin on Fri Dec 15 15:29:25 GMT 2023 , Edited by admin on Fri Dec 15 15:29:25 GMT 2023
|
PRIMARY | |||
|
C76542
Created by
admin on Fri Dec 15 15:29:25 GMT 2023 , Edited by admin on Fri Dec 15 15:29:25 GMT 2023
|
PRIMARY | |||
|
CHEMBL2106796
Created by
admin on Fri Dec 15 15:29:25 GMT 2023 , Edited by admin on Fri Dec 15 15:29:25 GMT 2023
|
PRIMARY | |||
|
100000083572
Created by
admin on Fri Dec 15 15:29:25 GMT 2023 , Edited by admin on Fri Dec 15 15:29:25 GMT 2023
|
PRIMARY |
ACTIVE MOIETY
SALT/SOLVATE (PARENT)
