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Details

Stereochemistry ABSOLUTE
Molecular Formula C18H22N4O4
Molecular Weight 358.3917
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of (2E)-N-[3,4-Dihydro-4-oxo-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide

SMILES

CN(C)C\C=C\C(=O)NC1=C(O[C@H]2CCOC2)C=C3NC=NC(=O)C3=C1

InChI

InChIKey=GSUSIQVMAQBROU-PCAWENJQSA-N
InChI=1S/C18H22N4O4/c1-22(2)6-3-4-17(23)21-15-8-13-14(19-11-20-18(13)24)9-16(15)26-12-5-7-25-10-12/h3-4,8-9,11-12H,5-7,10H2,1-2H3,(H,21,23)(H,19,20,24)/b4-3+/t12-/m0/s1

HIDE SMILES / InChI

Approval Year

Name Type Language
(2E)-N-[3,4-Dihydro-4-oxo-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide
Systematic Name English
(S,E)-4-(dimethylamino)-N-(4-hydroxy-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide
Systematic Name English
Afatinib impurity J
Common Name English
2-Butenamide, N-[3,4-dihydro-4-oxo-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-, (2E)-
Systematic Name English
Code System Code Type Description
CAS
1456696-14-2
Created by admin on Sat Dec 16 19:48:20 GMT 2023 , Edited by admin on Sat Dec 16 19:48:20 GMT 2023
PRIMARY
FDA UNII
8P652B3QLZ
Created by admin on Sat Dec 16 19:48:20 GMT 2023 , Edited by admin on Sat Dec 16 19:48:20 GMT 2023
PRIMARY
PUBCHEM
136295075
Created by admin on Sat Dec 16 19:48:20 GMT 2023 , Edited by admin on Sat Dec 16 19:48:20 GMT 2023
PRIMARY