DISODIUM CANTHARIDINATE

Details

Stereochemistry	MIXED
Molecular Formula	C10H14O5.2Na
Molecular Weight	260.1947
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 4
E/Z Centers	0
Charge	0
Stereo Comments	relative stereochemistry

SHOW SMILES / InChI

Structure Search

SMILES

[NaH].[NaH].C[C@@]1([C@@H]2CC[C@@H](O2)[C@@]1(C)C(O)=O)C(O)=O

InChI

InChIKey=GOGSWYVKNDVUJO-IVMHBOJMSA-N

InChI=1S/C10H14O5.2Na.2H/c1-9(7(11)12)5-3-4-6(15-5)10(9,2)8(13)14;;;;/h5-6H,3-4H2,1-2H3,(H,11,12)(H,13,14);;;;/t5-,6+,9+,10-;;;;

HIDE SMILES / InChI

Approval Year

Targets

Primary Target	Pharmacology	Potency
Serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform 11 Target ID: CHEMBL4703 Sources: https://www.ncbi.nlm.nih.gov/pubmed/1334551 \| https://www.ncbi.nlm.nih.gov/pubmed/17590861	Inhibitor 8297	50.0 nM [IC50]
Apoptosis 155 Target ID: map04210 Sources: https://www.ncbi.nlm.nih.gov/pubmed/29159945 \| https://www.ncbi.nlm.nih.gov/pubmed/10683193 \| https://www.ncbi.nlm.nih.gov/pubmed/29345422	Activator 1430
Serine/threonine protein phosphatase 1 (PP1) catalytic subunit (Mus musculus) 1 Target ID: Serine/threonine protein phosphatase 1 (PP1) catalytic subunit (Mus musculus) Sources: https://www.ncbi.nlm.nih.gov/pubmed/8240393	Inhibitor 8297	562.0 nM [IC50]

PubMed

Title	Date	PubMed
Hamster pancreatic beta cell lines with altered sensitivity towards apoptotic signalling by phosphatase inhibitors.	2000 Feb	10683193
Cantharidic acid induces apoptosis of human leukemic HL-60 cells via c-Jun N-terminal kinase-regulated caspase-8/-9/-3 activation pathway.	2018 Apr	29345422
Cantharidic acid induces apoptosis through the p38 MAPK signaling pathway in human hepatocellular carcinoma.	2018 Mar	29159945

Name

Type

Language

DISODIUM CANTHARIDINATE

Common Name

English

DISODIUM CANTHARIDIN

Common Name

English

7-OXABICYCLO(2.2.1)HEPTANE-2,3-DICARBOXYLIC ACID, 2,3-DIMETHYL-, DISODIUM SALT

Systematic Name

English

Disodium cantharidinate [WHO-DD]

Common Name

English

SODIUM CANTHARIDATE

Common Name

English

7-OXABICYCLO(2.2.1)HEPTANE-2,3-DICARBOXYLIC ACID, 2,3-DIMETHYL-, DISODIUM SALT, (1R,2S,3R,4S)-REL-

Systematic Name

English

7-OXABICYCLO(2.2.1)HEPTANE-2,3-DICARBOXYLIC ACID, 2,3-DIMETHYL-, DISODIUM SALT, (EXO,EXO)-

Systematic Name

English

CANTHARIDIN DISODIUM

Common Name

English

DISODIUM CANTHARIDATE

Common Name

English

7-OXABICYCLO(2.2.1)HEPTANE-2,3-DICARBOXYLIC ACID, 2,3-DIMETHYL-, SODIUM SALT (1:2), (1R,2S,3R,4S)-REL-

Systematic Name

English

Code System Code Type Description

FDA UNII

8OIF7X5MK8

Created by admin on Sat Dec 16 13:59:32 GMT 2023 , Edited by admin on Sat Dec 16 13:59:32 GMT 2023

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SMS_ID

100000183247

Created by admin on Sat Dec 16 13:59:32 GMT 2023 , Edited by admin on Sat Dec 16 13:59:32 GMT 2023

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PUBCHEM

121474

Created by admin on Sat Dec 16 13:59:32 GMT 2023 , Edited by admin on Sat Dec 16 13:59:32 GMT 2023

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CAS

1465-77-6

Created by admin on Sat Dec 16 13:59:32 GMT 2023 , Edited by admin on Sat Dec 16 13:59:32 GMT 2023

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SUBSTANCE RECORD


					8OIF7X5MK8

DISODIUM CANTHARIDINATE