Details
Stereochemistry | RACEMIC |
Molecular Formula | C6H8FN3O3 |
Molecular Weight | 188.147 |
Optical Activity | ( + / - ) |
Defined Stereocenters | 0 / 1 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(C[18F])CN1C=CN=C1[N+]([O-])=O
InChI
InChIKey=HIIJZYSUEJYLMX-JZRMKITLSA-N
InChI=1S/C6H8FN3O3/c7-3-5(11)4-9-2-1-8-6(9)10(12)13/h1-2,5,11H,3-4H2/i7-1
Fluoromisonidazole F-18 ([F-18] FMISO) is used as a positron emission tomography (PET) radiotracer for imaging. It is generated by labeling fluoromisonidazole with fluorine-18. It is the most widely used nitroimidazole imaging agent for use as a non-invasive way to localize and quantify hypoxia. [18F] decays by positron emission. FMISO binds covalently to cellular molecules at rates that are inversely proportional to intracellular oxygen concentration. In hypoxic cells, FMISO is trapped, which is the basis for the use of this tracer to measure hypoxia.
Approval Year
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Classification Tree | Code System | Code | ||
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FDA ORPHAN DRUG |
521116
Created by
admin on Fri Dec 15 15:42:22 GMT 2023 , Edited by admin on Fri Dec 15 15:42:22 GMT 2023
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FDA ORPHAN DRUG |
509715
Created by
admin on Fri Dec 15 15:42:22 GMT 2023 , Edited by admin on Fri Dec 15 15:42:22 GMT 2023
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Code System | Code | Type | Description | ||
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DB14830
Created by
admin on Fri Dec 15 15:42:22 GMT 2023 , Edited by admin on Fri Dec 15 15:42:22 GMT 2023
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PRIMARY | |||
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100000168508
Created by
admin on Fri Dec 15 15:42:22 GMT 2023 , Edited by admin on Fri Dec 15 15:42:22 GMT 2023
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PRIMARY | |||
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FMISO
Created by
admin on Fri Dec 15 15:42:22 GMT 2023 , Edited by admin on Fri Dec 15 15:42:22 GMT 2023
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PRIMARY | |||
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DTXSID801313634
Created by
admin on Fri Dec 15 15:42:22 GMT 2023 , Edited by admin on Fri Dec 15 15:42:22 GMT 2023
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PRIMARY | |||
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450173
Created by
admin on Fri Dec 15 15:42:22 GMT 2023 , Edited by admin on Fri Dec 15 15:42:22 GMT 2023
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PRIMARY | |||
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8MSY49469G
Created by
admin on Fri Dec 15 15:42:22 GMT 2023 , Edited by admin on Fri Dec 15 15:42:22 GMT 2023
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PRIMARY | |||
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SUB182026
Created by
admin on Fri Dec 15 15:42:22 GMT 2023 , Edited by admin on Fri Dec 15 15:42:22 GMT 2023
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PRIMARY | |||
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104613-87-8
Created by
admin on Fri Dec 15 15:42:22 GMT 2023 , Edited by admin on Fri Dec 15 15:42:22 GMT 2023
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PRIMARY | |||
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C52180
Created by
admin on Fri Dec 15 15:42:22 GMT 2023 , Edited by admin on Fri Dec 15 15:42:22 GMT 2023
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PRIMARY |
ACTIVE MOIETY