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Details

Stereochemistry ACHIRAL
Molecular Formula C19H20F3NO
Molecular Weight 335.3634
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of BOXIDINE

SMILES

FC(F)(F)C1=CC=C(C=C1)C2=CC=C(OCCN3CCCC3)C=C2

InChI

InChIKey=FOCUKKUAGZPPCU-UHFFFAOYSA-N
InChI=1S/C19H20F3NO/c20-19(21,22)17-7-3-15(4-8-17)16-5-9-18(10-6-16)24-14-13-23-11-1-2-12-23/h3-10H,1-2,11-14H2

HIDE SMILES / InChI

Description

Boxidine (1-[2-[[4′-(Trifluoromethyl)-4-biphenylyl]oxy]ethyl]pyrrolidine) is an inhibitor of 3β-hydroxysteroid-Δ7-reductase (DHCR7) thereby it affects cholesterol biosynthesis. Boxidine induces the accumulation of desmosterol.

Approval Year

Unknown
149124
Name Type Language
BOXIDINE
INN   USAN  
INN   USAN  
Official Name English
CL 65205
Preferred Name English
1-(2-((4'-(TRIFLUOROMETHYL)-4-BIPHENYLYL)OXY)ETHYL)PYRROLIDINE
Systematic Name English
boxidine [INN]
Common Name English
PYRROLIDINE, 1-(2-((4'-(TRIFLUOROMETHYL)(1,1'-BIPHENYL)-4-YL)OXY)ETHYL)-
Systematic Name English
CL-65205
Code English
BOXIDINE [USAN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C29703
Created by admin on Wed Apr 02 09:30:38 GMT 2025 , Edited by admin on Wed Apr 02 09:30:38 GMT 2025
Code System Code Type Description
SMS_ID
100000088657
Created by admin on Wed Apr 02 09:30:38 GMT 2025 , Edited by admin on Wed Apr 02 09:30:38 GMT 2025
PRIMARY
MESH
C100055
Created by admin on Wed Apr 02 09:30:38 GMT 2025 , Edited by admin on Wed Apr 02 09:30:38 GMT 2025
PRIMARY
PUBCHEM
31742
Created by admin on Wed Apr 02 09:30:38 GMT 2025 , Edited by admin on Wed Apr 02 09:30:38 GMT 2025
PRIMARY
EPA CompTox
DTXSID70145896
Created by admin on Wed Apr 02 09:30:38 GMT 2025 , Edited by admin on Wed Apr 02 09:30:38 GMT 2025
PRIMARY
INN
2392
Created by admin on Wed Apr 02 09:30:38 GMT 2025 , Edited by admin on Wed Apr 02 09:30:38 GMT 2025
PRIMARY
NCI_THESAURUS
C91025
Created by admin on Wed Apr 02 09:30:38 GMT 2025 , Edited by admin on Wed Apr 02 09:30:38 GMT 2025
PRIMARY
EVMPD
SUB05879MIG
Created by admin on Wed Apr 02 09:30:38 GMT 2025 , Edited by admin on Wed Apr 02 09:30:38 GMT 2025
PRIMARY
ChEMBL
CHEMBL1615348
Created by admin on Wed Apr 02 09:30:38 GMT 2025 , Edited by admin on Wed Apr 02 09:30:38 GMT 2025
PRIMARY
CAS
10355-14-3
Created by admin on Wed Apr 02 09:30:38 GMT 2025 , Edited by admin on Wed Apr 02 09:30:38 GMT 2025
PRIMARY
FDA UNII
8MJ40K4117
Created by admin on Wed Apr 02 09:30:38 GMT 2025 , Edited by admin on Wed Apr 02 09:30:38 GMT 2025
PRIMARY
ACTIVE MOIETY
Structure of BOXIDINE
SALT/SOLVATE (PARENT)
Structure of BOXIDINE HYDROCHLORIDE
NIH
NCATS
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