NERAL

Details

Stereochemistry	ACHIRAL
Molecular Formula	C10H16O
Molecular Weight	152.2334
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)=CCC\C(C)=C/C=O

InChI

InChIKey=WTEVQBCEXWBHNA-YFHOEESVSA-N

InChI=1S/C10H16O/c1-9(2)5-4-6-10(3)7-8-11/h5,7-8H,4,6H2,1-3H3/b10-7-

HIDE SMILES / InChI

Approval Year

PubMed

Title	Date	PubMed
Antifungal properties of essential oils and their main components upon Cryptococcus neoformans.	1994 Dec	7739729
Assessment of estrogenic activity in some common essential oil constituents.	2002 Nov	12495555
Utilization of geraniol is dependent on molybdenum in Pseudomonas aeruginosa: evidence for different metabolic routes for oxidation of geraniol and citronellol.	2005 Jul	16000717
Analysis of the enzymatic formation of citral in the glands of sweet basil.	2006 Apr 15	16150417
Use of IL-8 release and p38 MAPK activation in THP-1 cells to identify allergens and to assess their potency in vitro.	2010 Sep	20541004
A new in vitro method for identifying chemical sensitizers combining peptide binding with ARE/EpRE-mediated gene expression in human skin cells.	2010 Sep	20491607
HPLC-FLD methods to quantify chloroaluminum phthalocyanine in nanoparticles, plasma and tissue: application in pharmacokinetic and biodistribution studies.	2011 Aug 25	21596512
An in vitro test to screen skin sensitizers using a stable THP-1-derived IL-8 reporter cell line, THP-G8.	2011 Dec	21920952
B cell increases and ex vivo IL-2 production as secondary endpoints for the detection of sensitizers in non-radioisotopic local lymph node assay using flow cytometry.	2012 Mar 25	22245253
Fumigant antifungal activity of Myrtaceae essential oils and constituents from Leptospermum petersonii against three Aspergillus species.	2012 Sep 3	22945026
Differentiation of skin sensitizers from irritant chemicals by interleukin-1α and macrophage inflammatory protein-2 in murine keratinocytes.	2013 Jan 10	23178550
A screen for disruptors of the retinol (vitamin A) signaling pathway.	2013 Jun	23696197
Genes specifically modulated in sensitized skins allow the detection of sensitizers in a reconstructed human skin model. Development of the SENS-IS assay.	2015 Jun	25724174
Chemical allergens stimulate human epidermal keratinocytes to produce lymphangiogenic vascular endothelial growth factor.	2015 Mar 1	25617811
Dual regulation of skin sensitizer-induced HMOX1 expression by Bach1 and Nrf2: Comparison to regulation of the AKR1C2-ARE element in the KeratinoSens cell line.	2015 Nov 1	26244607

Patents

Name

Type

Language

NERAL

Systematic Name

English

CITRAL NERAL [MI]

Common Name

English

CITRAL-B

Common Name

English

CIS-CITRAL

Common Name

English

CITRAL NERAL

Systematic Name

English

CITRAL B

Common Name

English

(2Z)-3,7-DIMETHYLOCTA-2,6-DIENAL

Systematic Name

English

Code System Code Type Description

EVMPD

SUB62725