Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C25H33NO4.ClH |
Molecular Weight | 447.995 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 7 / 7 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.[H][C@@]12OC3=C(O)C=CC4=C3[C@@]15CCN(C)[C@]([H])(C4)[C@@]56C[C@]([H])([C@](C)(O)CCC)[C@]2(OC)C=C6
InChI
InChIKey=JNHPUZURWFYYHW-DTUSRQQPSA-N
InChI=1S/C25H33NO4.ClH/c1-5-8-22(2,28)17-14-23-9-10-25(17,29-4)21-24(23)11-12-26(3)18(23)13-15-6-7-16(27)20(30-21)19(15)24;/h6-7,9-10,17-18,21,27-28H,5,8,11-14H2,1-4H3;1H/t17-,18-,21-,22-,23-,24+,25-;/m1./s1
Etorphine was the first potent opiate agonist employed primarily for use in non-domestic and wild species. Etorphine was 500 times as potent as morphine, with a very rapid onset and short duration of action. In morphine-dependent subjects, etorphine suppressed abstinence but for a shorter period than morphine. Etorphine is a full opiate agonist and binds to multiple opiate sites in the central nervous system. It is believed to produce its clinical effects through binding the µ-, δ-, and κ- opiate sites. It has a potent effect on depressing the respiratory centers of the CNS thus resulting in apnea being commonly seen in immobilized animals. Etorphine revolutionized the ability of biologists and veterinarians to safely capture and restrain many species that previously could not be handled. Etorphine is not currently commercially available due to lack of production by the manufacturer.
CNS Activity
Approval Year
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Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C67413
Created by
admin on Fri Dec 15 15:36:11 GMT 2023 , Edited by admin on Fri Dec 15 15:36:11 GMT 2023
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CFR |
21 CFR 522.883
Created by
admin on Fri Dec 15 15:36:11 GMT 2023 , Edited by admin on Fri Dec 15 15:36:11 GMT 2023
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DEA NO. |
9059
Created by
admin on Fri Dec 15 15:36:11 GMT 2023 , Edited by admin on Fri Dec 15 15:36:11 GMT 2023
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Code System | Code | Type | Description | ||
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DTXSID00160254
Created by
admin on Fri Dec 15 15:36:11 GMT 2023 , Edited by admin on Fri Dec 15 15:36:11 GMT 2023
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Etorphine hydrochloride
Created by
admin on Fri Dec 15 15:36:11 GMT 2023 , Edited by admin on Fri Dec 15 15:36:11 GMT 2023
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13764-49-3
Created by
admin on Fri Dec 15 15:36:11 GMT 2023 , Edited by admin on Fri Dec 15 15:36:11 GMT 2023
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DBSALT000825
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admin on Fri Dec 15 15:36:11 GMT 2023 , Edited by admin on Fri Dec 15 15:36:11 GMT 2023
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8CBE01N748
Created by
admin on Fri Dec 15 15:36:11 GMT 2023 , Edited by admin on Fri Dec 15 15:36:11 GMT 2023
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23623749
Created by
admin on Fri Dec 15 15:36:11 GMT 2023 , Edited by admin on Fri Dec 15 15:36:11 GMT 2023
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237-364-7
Created by
admin on Fri Dec 15 15:36:11 GMT 2023 , Edited by admin on Fri Dec 15 15:36:11 GMT 2023
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300000023792
Created by
admin on Fri Dec 15 15:36:11 GMT 2023 , Edited by admin on Fri Dec 15 15:36:11 GMT 2023
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C83705
Created by
admin on Fri Dec 15 15:36:11 GMT 2023 , Edited by admin on Fri Dec 15 15:36:11 GMT 2023
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PRIMARY |
ACTIVE MOIETY
SUBSTANCE RECORD