Stereochemistry | ACHIRAL |
Molecular Formula | C17H17F3N6O2 |
Molecular Weight | 394.3511 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CC1(C)CN(C(=O)N1)C2=NC=C(C(=O)NC3=CC=CC(=C3)C(F)(F)F)C(N)=N2
InChI
InChIKey=FUSNOPLQVRUIIM-UHFFFAOYSA-N
InChI=1S/C17H17F3N6O2/c1-16(2)8-26(15(28)25-16)14-22-7-11(12(21)24-14)13(27)23-10-5-3-4-9(6-10)17(18,19)20/h3-7H,8H2,1-2H3,(H,23,27)(H,25,28)(H2,21,22,24)
Imanixil (also known as HOE-402) was developed as a potent cholesterol-lowering compound, which inhibits VLDL production, and consequently attenuates atherosclerosis development. This drug participated in phase I clinical trial for the treatment of hyperlipidemia, however, this study was discontinued.