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Details

Stereochemistry ACHIRAL
Molecular Formula C14H13ClN4O2
Molecular Weight 304.732
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of AROFYLLINE

SMILES

CCCN1C(=O)N(C2=C(NC=N2)C1=O)C3=CC=C(Cl)C=C3

InChI

InChIKey=GVTLDPJNRVMCAL-UHFFFAOYSA-N
InChI=1S/C14H13ClN4O2/c1-2-7-18-13(20)11-12(17-8-16-11)19(14(18)21)10-5-3-9(15)4-6-10/h3-6,8H,2,7H2,1H3,(H,16,17)

HIDE SMILES / InChI
Arofylline, a phosphodiesterase 4 inhibitor, participated in clinical trials phase III to treat patients with chronic obstructive pulmonary disease. Besides, in Spain, this drug participated in clinical trials for patients with asthma.

Approval Year

PubMed

PubMed

TitleDatePubMed
Evidence-based veterinary dermatology: a systematic review of the pharmacotherapy of canine atopic dermatitis.
2003 Jun
Biological targets for therapeutic interventions in COPD: clinical potential.
2006

Sample Use Guides

Unknown
Route of Administration: Other
Name Type Language
AROFYLLINE
INN   USAN  
USAN   INN  
Official Name English
LAS 31025
Code English
AROFYLLINE [USAN]
Common Name English
3-(P-CHLOROPHENYL)-1-PROPYLXANTHINE
Common Name English
arofylline [INN]
Common Name English
LAS-31025
Code English
Classification Tree Code System Code
NCI_THESAURUS C744
Created by admin on Sat Dec 16 16:20:13 GMT 2023 , Edited by admin on Sat Dec 16 16:20:13 GMT 2023
Code System Code Type Description
SMS_ID
100000086620
Created by admin on Sat Dec 16 16:20:13 GMT 2023 , Edited by admin on Sat Dec 16 16:20:13 GMT 2023
PRIMARY
PUBCHEM
166553
Created by admin on Sat Dec 16 16:20:13 GMT 2023 , Edited by admin on Sat Dec 16 16:20:13 GMT 2023
PRIMARY
INN
7464
Created by admin on Sat Dec 16 16:20:13 GMT 2023 , Edited by admin on Sat Dec 16 16:20:13 GMT 2023
PRIMARY
EVMPD
SUB05566MIG
Created by admin on Sat Dec 16 16:20:13 GMT 2023 , Edited by admin on Sat Dec 16 16:20:13 GMT 2023
PRIMARY
FDA UNII
87L38AY71R
Created by admin on Sat Dec 16 16:20:13 GMT 2023 , Edited by admin on Sat Dec 16 16:20:13 GMT 2023
PRIMARY
ChEMBL
CHEMBL1598450
Created by admin on Sat Dec 16 16:20:13 GMT 2023 , Edited by admin on Sat Dec 16 16:20:13 GMT 2023
PRIMARY
CAS
136145-07-8
Created by admin on Sat Dec 16 16:20:13 GMT 2023 , Edited by admin on Sat Dec 16 16:20:13 GMT 2023
PRIMARY
NCI_THESAURUS
C74223
Created by admin on Sat Dec 16 16:20:13 GMT 2023 , Edited by admin on Sat Dec 16 16:20:13 GMT 2023
PRIMARY
USAN
JJ-20
Created by admin on Sat Dec 16 16:20:13 GMT 2023 , Edited by admin on Sat Dec 16 16:20:13 GMT 2023
PRIMARY
EPA CompTox
DTXSID30159696
Created by admin on Sat Dec 16 16:20:13 GMT 2023 , Edited by admin on Sat Dec 16 16:20:13 GMT 2023
PRIMARY