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Details

Stereochemistry ABSOLUTE
Molecular Formula C34H55NO3
Molecular Weight 525.8054
Optical Activity UNSPECIFIED
Defined Stereocenters 6 / 6
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ICI-164384

SMILES

[H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@]3([H])C4=CC=C(O)C=C4C[C@@H](CCCCCCCCCCC(=O)N(C)CCCC)[C@@]23[H]

InChI

InChIKey=BVVFOLSZMQVDKV-KXQIQQEYSA-N
InChI=1S/C34H55NO3/c1-4-5-22-35(3)32(38)15-13-11-9-7-6-8-10-12-14-25-23-26-24-27(36)16-17-28(26)29-20-21-34(2)30(33(25)29)18-19-31(34)37/h16-17,24-25,29-31,33,36-37H,4-15,18-23H2,1-3H3/t25-,29-,30+,31+,33-,34+/m1/s1

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
2,3,7,8-Tetrachlorodibenzo-p-dioxin-induced thymic atrophy and lymphocyte stem cell alterations by mechanisms independent of the estrogen receptor.
1994 Jun 1
Effect of cadmium on estrogen receptor levels and estrogen-induced responses in human breast cancer cells.
1994 Jun 17
Influence of xenobiotics on rainbow trout liver estrogen receptor and vitellogenin gene expression.
1995 Oct
Estrogenic potential of certain pyrethroid compounds in the MCF-7 human breast carcinoma cell line.
1999 Mar
Differential estrogen receptor binding of estrogenic substances: a species comparison.
2000 Nov 15
Pure antiestrogens and breast cancer.
2001
Transcriptional activation of heat shock protein 27 gene expression by 17beta-estradiol and modulation by antiestrogens and aryl hydrocarbon receptor agonists.
2001 Feb
The unusual binding properties of the third distinct teleost estrogen receptor subtype ERbetaa are accompanied by highly conserved amino acid changes in the ligand binding domain.
2004 Jun
Methyl mercury influences growth-related signaling in MCF-7 breast cancer cells.
2005 Feb
Serum free BG-1 cell proliferation assay: a sensitive method for determining organochlorine pesticide estrogen receptor activation at the nanomolar range.
2006 Apr
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.
2006 Nov
Downregulation of SIAH2, an ubiquitin E3 ligase, is associated with resistance to endocrine therapy in breast cancer.
2009 Jul
Comparison of relative binding affinities to fish and mammalian estrogen receptors: the regulatory implications.
2010 Feb 15
Olfactomedin-4 regulation by estrogen in the human endometrium requires epidermal growth factor signaling.
2010 Nov
Patents
Name Type Language
ICI-164384
Common Name English
N-BUTYL-11-((17.BETA.)-3,17-DIHYDROXYESTRA-1,3,5(10)-TRIEN-7-YL)-N-METHYLUNDECANAMIDE
Systematic Name English
ICI 164384
Common Name English
UNDECANAMIDE, N-BUTYL-11-((17.BETA.)-3,17-DIHYDROXYESTRA-1,3,5(10)-TRIEN-7-YL)-N-METHYL-
Systematic Name English
ICI 164,384
Code English
Code System Code Type Description
FDA UNII
84LT43726C
Created by admin on Fri Dec 15 19:19:46 GMT 2023 , Edited by admin on Fri Dec 15 19:19:46 GMT 2023
PRIMARY
MESH
C051781
Created by admin on Fri Dec 15 19:19:46 GMT 2023 , Edited by admin on Fri Dec 15 19:19:46 GMT 2023
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WIKIPEDIA
ICI 164384
Created by admin on Fri Dec 15 19:19:46 GMT 2023 , Edited by admin on Fri Dec 15 19:19:46 GMT 2023
PRIMARY
EPA CompTox
DTXSID3022376
Created by admin on Fri Dec 15 19:19:46 GMT 2023 , Edited by admin on Fri Dec 15 19:19:46 GMT 2023
PRIMARY
CAS
98007-99-9
Created by admin on Fri Dec 15 19:19:46 GMT 2023 , Edited by admin on Fri Dec 15 19:19:46 GMT 2023
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CHEBI
40710
Created by admin on Fri Dec 15 19:19:46 GMT 2023 , Edited by admin on Fri Dec 15 19:19:46 GMT 2023
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PUBCHEM
104772
Created by admin on Fri Dec 15 19:19:46 GMT 2023 , Edited by admin on Fri Dec 15 19:19:46 GMT 2023
PRIMARY
DRUG BANK
DB03860
Created by admin on Fri Dec 15 19:19:46 GMT 2023 , Edited by admin on Fri Dec 15 19:19:46 GMT 2023
PRIMARY