Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C10H14N2O2S |
| Molecular Weight | 226.295 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
C[C@@H](S)[C@@H](CC1=CN=C(N)C=C1)C(O)=O
InChI
InChIKey=GYIYAOUGKJSCCG-HTRCEHHLSA-N
InChI=1S/C10H14N2O2S/c1-6(15)8(10(13)14)4-7-2-3-9(11)12-5-7/h2-3,5-6,8,15H,4H2,1H3,(H2,11,12)(H,13,14)/t6-,8-/m1/s1
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Laudanosine and atracurium concentrations in a patient receiving long-term atracurium infusion. | 1998 Jan |
|
| Blockade and activation of the human neuronal nicotinic acetylcholine receptors by atracurium and laudanosine. | 2001 Apr |
|
| Concentration-effect relationship of cisatracurium at three different dose levels in the anesthetized patient. | 2001 Aug |
|
| The pharmacokinetics of cisatracurium in patients with acute respiratory distress syndrome. | 2001 Aug |
|
| Pharmacokinetic-pharmacodynamic modeling of atracurium in intensive care patients. | 2001 Jan |
|
| Inhibitory effects of ethaverine, a homologue of papaverine, on monoamine oxidase activity in mouse brain. | 2001 Jul |
|
| Does ester hydrolysis change the in vitro degradation rate of cisatracurium and atracurium? | 2002 Apr |
|
| Pharmacodynamics and atracurium and laudanosine concentrations during a fixed continuous infusion of atracurium in mechanically ventilated patients with acute respiratory distress syndrome. | 2002 Aug |
|
| Laudanosine, an atracurium and cisatracurium metabolite. | 2002 Jul |
|
| Colominic acid: a novel chiral selector for capillary electrophoresis of basic drugs. | 2002 Jul 12 |
|
| Cerebrospinal fluid concentrations of atracurium, laudanosine and vecuronium following clinical subarachnoid hemorrhage. | 2002 Nov |
|
| Aporphine alkaloids from Guatteria spp. with leishmanicidal activity. | 2003 Jul |
|
| The possible neuroprotective effect of laudanosine, an atracurium and cisatracurium metabolite. | 2003 Jul |
|
| Transformation of opium poppy (Papaver somniferum L.) with antisense berberine bridge enzyme gene (anti-bbe) via somatic embryogenesis results in an altered ratio of alkaloids in latex but not in roots. | 2004 Dec |
|
| Instability of pancuronium in postmortem blood and liver taken after a fatal intramuscular Pavulon injection. | 2004 Jul 16 |
|
| The insulin pump as murder weapon: a case report. | 2004 Jun |
|
| Identification and quantitation of six non-depolarizing neuromuscular blocking agents by LC-MS in biological fluids. | 2004 Mar |
|
| The GC-MS detection and characterization of reticuline as a marker of opium use. | 2004 Mar 10 |
|
| The GC-MS detection and characterization of reticuline as a marker of opium use. | 2004 May 28 |
|
| The efficient synthesis of morphinandienone alkaloids by using a combination of hypervalent iodine(III) reagent and heteropoly acid. | 2004 Oct 11 |
|
| Perinatal neuroprotection by muscle relaxants against hypoxic-ischemic lesions: is it a possible hypothesis? | 2005 Aug |
|
| SK channels control the firing pattern of midbrain dopaminergic neurons in vivo. | 2005 Dec |
|
| Synthesis and biological evaluation of N-methyl-laudanosine iodide analogues as potential SK channel blockers. | 2005 Feb 15 |
|
| Evaluation of benzyltetrahydroisoquinolines as ligands for neuronal nicotinic acetylcholine receptors. | 2005 Sep |
|
| Chiral separation of norlaudanosoline, laudanosoline, laudanosine, chlorthalidone, and three benzoin derivatives using amino acid based molecular micelles. | 2006 Feb |
|
| Anesthesiologist suicide with atracurium. | 2006 Mar |
|
| Applicability of ultra-performance liquid chromatography-tandem mass spectrometry for heroin profiling. | 2008 Apr 25 |
|
| Synthesis of carbon-11 labeled 1-(3,4-dimethoxybenzyl)-2,2-dimethyl-1,2,3,4-tetrahydroisoquinolinium derivatives as new potential PET SKCa channel imaging agents. | 2008 Feb |
|
| Use of intrathecal and intravenous clonidine in a case of severe tetanus with acute renal failure. | 2009 Apr |
|
| Laudanosine has no effects on respiratory activity but induces non-respiratory excitement activity in isolated brainstem-spinal cord preparation of neonatal rats. | 2010 |
|
| The biosynthesis of papaverine proceeds via (S)-reticuline. | 2010 Aug |
|
| Determination of atracurium, cisatracurium and mivacurium with their impurities in pharmaceutical preparations by liquid chromatography with charged aerosol detection. | 2010 Feb 19 |
|
| Evaluation of the enantioselectivity of glycogen-based dual chiral selector systems towards basic drugs in capillary electrophoresis. | 2010 Nov 5 |
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87609775
Created by
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DB05712
Created by
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84KQ4M4N8B
Created by
admin on Sat Dec 16 12:12:50 GMT 2023 , Edited by admin on Sat Dec 16 12:12:50 GMT 2023
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775274-06-1
Created by
admin on Sat Dec 16 12:12:50 GMT 2023 , Edited by admin on Sat Dec 16 12:12:50 GMT 2023
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PRIMARY |
ACTIVE MOIETY
