TECHNETIUM TC-99M SIBOROXIME

First approved in 1973

Details

Stereochemistry	ACHIRAL
Molecular Formula	C16H29BN6O6.Cl.Tc
Molecular Weight	546.608
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	6
Charge	0

SHOW SMILES / InChI

Structure of TECHNETIUM TC-99M SIBOROXIME

Structure Search

SMILES

[Cl-].[99Tc+3].CC(C)C[B-](O\N=C(C)\C(C)=N\O)(O\N=C(C)\C(C)=N\O)O\N=C(C)\C(C)=N\[O-]

InChI

InChIKey=JQEZOWSBOAQDOO-UWKFYINPSA-L

InChI=1S/C16H30BN6O6.ClH.Tc/c1-10(2)9-17(27-21-14(6)11(3)18-24,28-22-15(7)12(4)19-25)29-23-16(8)13(5)20-26;;/h10,24-26H,9H2,1-8H3;1H;/q-1;;+3/p-2/b18-11+,19-12+,20-13+,21-14+,22-15+,23-16+;;/i;;1+1

HIDE SMILES / InChI

Description
Sources: https://www.hindawi.com/journals/stni/2014/839369/
Curator's Comment: description was created based on several sources, including https://www.ncbi.nlm.nih.gov/books/NBK215133/ | https://www.iaea.org/OurWork/ST/NE/NEFW/Technical-Areas/RRS/documents /mo99/WORKINGMATERIALSmo99CM.pdf | https://www.ncbi.nlm.nih.gov/pubmed/27854401

Molybdenum-99 (99Mo, half-life = 66 h) is a parent radionuclide of a diagnostic nuclear isotope. It decays in technetium-99 m (half-life = 6 h), which is used in over 30 million procedures per year around the world. Between 95 and 98 percent of Mo-99 is currently being produced using highly enriched uranium (HEU) targets. Other medical isotopes such as iodine-131 (I-131) and xenon-133 (Xe-133) are by-products of the Mo-99 production process and will be sufficiently available if Mo-99 is available.

Approval Year

Conditions

Condition	Modality	Highest Phase	Product
Unknown 2578
bone problems 43 Sources: https://www.drugs.com/cons/osteolite.html	Diagnostic	Approved 8429	OSTEOLITE Approved Use Unknown Launch Date 1977
osteogenesis 43 Sources: https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/018035s032lbl.pdf	Diagnostic	Approved 8429	DRAXIMAGE MDP-10 Approved Use MDP-25 (Kit for the Preparation of Technetium Tc 99m Medronate) may be used as a bone imaging agent to delineate areas of altered osteogenesis. Launch Date 1978

PubMed

Title	Date	PubMed
Future of low specific activity molybdenum-99/technetium-99m generator.	2012 Oct	22642420

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Name

Type

Language

TECHNETIUM TC-99M SIBOROXIME

Common Name

English

SQ 32,097

Code

English

TECHNETIUM (99MTC) SIBOROXIME

Official Name

English

technetium (⁹⁹mTc) siboroxime [INN]

Common Name

English

SQ-32097

Code

English

TECHNETIUM TC 99M SIBOROXIME

Official Name

English

TECHNETIUM TC 99M SIBOROXIME [USAN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C2124