5,6-DICHLORORIBOFURANOSYLBENZIMIDAZOLE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C12H12Cl2N2O4
Molecular Weight	319.141
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of 5,6-DICHLORORIBOFURANOSYLBENZIMIDAZOLE

Structure Search

SMILES

OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=NC3=C2C=C(Cl)C(Cl)=C3

InChI

InChIKey=XHSQDZXAVJRBMX-DDHJBXDOSA-N

InChI=1S/C12H12Cl2N2O4/c13-5-1-7-8(2-6(5)14)16(4-15-7)12-11(19)10(18)9(3-17)20-12/h1-2,4,9-12,17-19H,3H2/t9-,10-,11-,12-/m1/s1

HIDE SMILES / InChI

Approval Year

Targets

Targets

Primary Target	Pharmacology	Condition	Potency
Casein kinase 2 (Bos taurus) 1 Target ID: Casein kinase 2 (Bos taurus) Sources: https://www.ncbi.nlm.nih.gov/pubmed/2803263	Inhibitor 8297		7.0 µM [IC50]
CDK7/Cyclin H/MNAT1 1 Target ID: CHEMBL3038473 Sources: https://www.ncbi.nlm.nih.gov/pubmed/10023686	Inhibitor 8297		18.0 µM [IC50]
CDK8/Cyclin C 2 Target ID: CHEMBL3038474 Sources: https://www.ncbi.nlm.nih.gov/pubmed/10023686	Inhibitor 8297		17.0 µM [IC50]

Name

Type

Language

5,6-DICHLORORIBOFURANOSYLBENZIMIDAZOLE

Common Name

English

NSC-401575

Code

English

5,6-DICHLORO-1-.BETA.-D-RIBOFURANOSYL-1H-BENZIMIDAZOLE

Systematic Name

English

DICHLORORIBOFURANOSYLBENZIMIDAZOLE

Common Name

English

5,6-DICHLOROBENZIMIDAZOLE 1-.BETA.-D-RIBOFURANOSIDE

Systematic Name

English

1-.BETA.-D-RIBOFURANOSYL-5,6-DICHLOROBENZIMIDAZOLE

Systematic Name

English

BENZIMIDAZOLE, 5,6-DICHLORO-1-D-RIBOFURANOSYL-

Systematic Name

English

5,6-DICHLORO-1-(.BETA.-D-RIBOFURANOSYL)BENZIMIDAZOLE

Systematic Name

English

BENZIMIDAZOLE, 5,6-DICHLORO-1-.BETA.-D-RIBOFURANOSYL-

Systematic Name

English

Code System Code Type Description

SMS_ID

100000182931

Created by admin on Sat Dec 16 13:28:37 GMT 2023 , Edited by admin on Sat Dec 16 13:28:37 GMT 2023

PRIMARY

CAS

909276-76-2

Created by admin on Sat Dec 16 13:28:37 GMT 2023 , Edited by admin on Sat Dec 16 13:28:37 GMT 2023

SUPERSEDED

EVMPD

SUB197205

Created by admin on Sat Dec 16 13:28:37 GMT 2023 , Edited by admin on Sat Dec 16 13:28:37 GMT 2023

PRIMARY

EPA CompTox

DTXSID50967472

Created by admin on Sat Dec 16 13:28:37 GMT 2023 , Edited by admin on Sat Dec 16 13:28:37 GMT 2023

PRIMARY

WIKIPEDIA

5,6-Dichloro-1-beta-D-ribofuranosylbenzimidazole

Created by admin on Sat Dec 16 13:28:37 GMT 2023 , Edited by admin on Sat Dec 16 13:28:37 GMT 2023

PRIMARY

FDA UNII

8153319T3Q

Created by admin on Sat Dec 16 13:28:37 GMT 2023 , Edited by admin on Sat Dec 16 13:28:37 GMT 2023

PRIMARY

NSC

401575

Created by admin on Sat Dec 16 13:28:37 GMT 2023 , Edited by admin on Sat Dec 16 13:28:37 GMT 2023

PRIMARY

CAS

53-85-0

Created by admin on Sat Dec 16 13:28:37 GMT 2023 , Edited by admin on Sat Dec 16 13:28:37 GMT 2023

PRIMARY

CAS

1821045-35-5

Created by admin on Sat Dec 16 13:28:37 GMT 2023 , Edited by admin on Sat Dec 16 13:28:37 GMT 2023

SUPERSEDED

DRUG BANK

DB08473

Created by admin on Sat Dec 16 13:28:37 GMT 2023 , Edited by admin on Sat Dec 16 13:28:37 GMT 2023

PRIMARY

PUBCHEM

5894

Created by admin on Sat Dec 16 13:28:37 GMT 2023 , Edited by admin on Sat Dec 16 13:28:37 GMT 2023

PRIMARY

SUBSTANCE RECORD


					8153319T3Q

5,6-DICHLORORIBOFURANOSYLBENZIMIDAZOLE