| Stereochemistry | ACHIRAL |
| Molecular Formula | C14H8Br2F3NO2 |
| Molecular Weight | 439.022 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC1=C(C=C(Br)C=C1Br)C(=O)NC2=CC=CC(=C2)C(F)(F)F
InChI
InChIKey=VYKKDKFTDMVOBU-UHFFFAOYSA-N
InChI=1S/C14H8Br2F3NO2/c15-8-5-10(12(21)11(16)6-8)13(22)20-9-3-1-2-7(4-9)14(17,18)19/h1-6,21H,(H,20,22)
Antimicrobial agent Fluorosalan is classified as Category II for use as antiseptic handwash, healthcare personnel handwash, patient preoperative skin preoperative skin preparation, and surgical hand scrub products. In the 1994 TFM (59 FR 31402 at 31435-31436), FDA proposed that the active ingredient fluorosalan be found not GRAS/GRAE for the uses referred to in the 1994 TFM as antiseptic hand wash and health care personnel hand wash.
Originator
Approval Year
Conditions
| Condition | Modality | Targets | Highest Phase | Product |
|---|---|---|---|---|
Sourcing
Sample Use Guides
The intracellular ATP content of two human cervical cancer cell lines, ME180 and HeLa, was measured after the treatment of the compounds for 5–72 h. After 5 h treatment, Fluorosalan showed no inhibitory effect on cell growth. After 24–72 h treatment, Fluorosalan significantly inhibited the growth of ME180 cells (IC50 24h: 9.0uM, 48h: 2.7uM, 72h: 1.3uM) and HeLa (IC50 24h: 3.1uM, 48h: 2.1uM, 72h: 3.3uM).
ACTIVE MOIETY
