CARBOSTYRIL

Details

Stereochemistry	ACHIRAL
Molecular Formula	C9H7NO
Molecular Weight	145.158
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

O=C1NC2=C(C=CC=C2)C=C1

InChI

InChIKey=LISFMEBWQUVKPJ-UHFFFAOYSA-N

InChI=1S/C9H7NO/c11-9-6-5-7-3-1-2-4-8(7)10-9/h1-6H,(H,10,11)

HIDE SMILES / InChI

Approval Year

PubMed

Title	Date	PubMed
[Antimicrobially effective compounded medications. Clinical value and critical comments].	2005-08	15933865
6-hydroxyquinoline-N-oxides: a new class of "super" photoacids.	2005-06-15	15941289
Discovery of powerful uranyl ligands from efficient synthesis and screening.	2005-06-06	15809989
Benzimidazolones and indoles as non-thiol farnesyltransferase inhibitors based on tipifarnib scaffold: synthesis and activity.	2005-06-02	15911281
Rapid simultaneous determination of metabolic clearance of multiple compounds catalyzed in vitro by recombinant human UDP-glucuronosyltransferases.	2005-06-01	15866534
Inhibition of mutation and combating the evolution of antibiotic resistance.	2005-06	15869329
Microwave-assisted multistep synthesis of functionalized 4-arylquinolin-2(1H)-ones using palladium-catalyzed cross-coupling chemistry.	2005-05-13	15876072
2-Oxoquinoline 8-monooxygenase oxygenase component: active site modulation by Rieske-[2Fe-2S] center oxidation/reduction.	2005-05	15893671
Design, synthesis, and activity of achiral analogs of 2-quinolones and indoles as non-thiol farnesyltransferase inhibitors.	2005-04-15	15808463
Synthesis of 5-substituted-1H-indol-2-yl-1H-quinolin-2-ones: a novel class of KDR kinase inhibitors.	2005-04-01	15787543
Development of a real-time fluorescence resonance energy transfer PCR to identify the main pathogenic Campylobacter spp.	2005-04	15760424
Design, microwave-assisted synthesis, and photophysical properties of small molecule organic antennas for luminescence resonance energy transfer.	2005-03-15	15762757
Parallel liquid-phase synthesis of N-substituted 6-aminosulfonyl-2-oxo-1,2-dihydroquinoline-4-carboxamide and 6-aminosulfonylquinoline-4-carboxamide derivatives.	2005-03-15	15762750
Molecular characterization of a multidrug-resistant strain of enteroinvasive Escherichia coli O164 isolated in Japan.	2005-03	15713611
Simultaneous determination of NSO-heterocycles, homocycles and their metabolites in groundwater of tar oil contaminated sites using LC with diode array UV and fluorescence detection.	2005-02-18	15782967
DNA gyrase gene in Neisseria gonorrhoeae as indicator for resistance to ciprofloxacin and species verification.	2005-02	15807943
Susceptibility of Campylobacter hyointestinalis subsp. hyointestinalis to antimicrobial agents and characterization of quinolone-resistant strains.	2005-02	15649999
Reactivity and transformation of antibacterial N-oxides in the presence of manganese oxide.	2005-01-15	15707060
The molecular epidemiology of Streptococcus pneumoniae with quinolone resistance mutations.	2005-01-15	15655739
Isolation and molecular characterization of fluoroquinolone-resistant Escherichia coli from poultry litter.	2005-01	15685943
An unusually high level of quinolone resistance associated with type II topoisomerase mutations in quinolone resistance-determining regions of Aeromonas caviae isolated from diarrhoeal patients.	2004-12	15567276
Electrophilic-induced cyclization reaction of hexahydroindolinone derivatives and its application toward the synthesis of (+/-)-erysotramidine.	2004-11-26	15549789
Bactericidal activity of garenoxacin tested by kill-curve methodology against wild type and QRDR mutant strains of Streptococcus pneumoniae.	2004-11	15541608
Excited-state proton transfer reactions of 10-hydroxycamptothecin.	2004-10-06	15453804
Fluoroquinolone resistance in penicillin-resistant Streptococcus pneumoniae clones, Spain.	2004-10	15504260
Genetic relatedness of ciprofloxacin-resistant Shigella dysenteriae type 1 strains isolated in south Asia.	2004-10	15347639
Carbostyril derivatives as antenna molecules for luminescent lanthanide chelates.	2004-09-16	15366964
Multidrug resistance associated with mexXY expression in clinical isolates of Pseudomonas aeruginosa from a Texas hospital.	2004-09	15380277
Antimicrobial resistance of Neisseria gonorrhoeae in Japan, 1993-2002: continuous increasing of ciprofloxacin-resistant isolates.	2004-09	15364300
Mechanisms of quinolone resistance and clonal relationship among Aeromonas salmonicida strains isolated from reared fish with furunculosis.	2004-09	15314197
Urine phenol and myeloperoxidase index: an observation in benzene exposed subjects.	2004-08	15370219
Active site geometry and substrate recognition of the molybdenum hydroxylase quinoline 2-oxidoreductase.	2004-08	15296736
Epidemiological characteristics and molecular basis of fluoroquinolone-resistant Neisseria gonorrhoeae strains isolated in Korea and nearby countries.	2004-08	15231766
Molecular basis of quinolone resistance in Escherichia coli from wild birds.	2004-07	15352551
Type II topoisomerase mutations in Bacillus anthracis associated with high-level fluoroquinolone resistance.	2004-07	15190035
Biradicals/zwitterions from thermolysis of enyne-isocyanates. Application to the synthesis of 2(1H)-pyridones, benzofuro[3,2-c]pyridin-1(2H)-ones, 2,5-dihydro-1H-pyrido[4,3-b]indol-1-ones, and related compounds.	2004-06-25	15202908
Entrapment and release of quinoline derivatives using a hydrogel of a low molecular weight gelator.	2004-06-18	15196751
Detection of mutations in the gyrA gene and class I integron from quinolone-resistant Salmonella enterica serovar Choleraesuis isolates in Taiwan.	2004-06-03	15145503
Quinolone resistance-determining region mutations and por type of Neisseria gonorrhoeae isolates: resistance surveillance and typing by molecular methodologies.	2004-06-01	15143477
The efficacy of some drugs with known antiprotozoal activity against Histomonas meleagridis in chickens.	2004-05-26	15135862
Characterization of a point mutation in the parC gene of Mycoplasma bovirhinis associated with fluoroquinolone resistance.	2004-05	15228551
[Study on the gene mutation of quinolone-resistant Mycobacterium tuberculosis isolated from Sichuan Province].	2004-05	15181822
Sequence and transcriptional analysis of a gene cluster of Pseudomonas putida 86 involved in quinoline degradation.	2004-04-28	15094204
Patterns of quinolone susceptibility in Campylobacter jejuni associated with different gyrA mutations.	2004-04	15203753
Hydrogen-bonded supramolecular motifs in 4,4'-bipyridinium 8-hydroxy-7-iodoquinoline-5-sulfonate dihydrate.	2004-04	15071237
Geographically dependent distribution of gyrA gene mutations at codons 83 and 87 in Salmonella Hadar, and a novel codon 81 Gly to His mutation in Salmonella Enteritidis.	2004-03	15153158
Ciprofloxacin-resistant Salmonella enterica Typhimurium and Choleraesuis from pigs to humans, Taiwan.	2004-01	15078598
Molecular characterization of clinical Streptococcus pneumoniae isolates with reduced susceptibility to fluoroquinolones emerging in Italy.	2004	15383164
Fluoroquinolone resistance in clinical isolates of Streptococcus pneumoniae from Asian countries: ANSORP study.	2004	15140392
Analysis of gyrA mutations in quinolone-resistant and -susceptible Campylobacter jejuni isolates from retail poultry and human clinical isolates by non-radioactive single-strand conformation polymorphism analysis and DNA sequencing.	2004	15078520

Patents

Name

Type

Language

CARBOSTYRIL

Common Name

English

NSC-156783

Preferred Name

English

2-QUINOLINOL

Systematic Name

English

2(1H)-QUINOLONE

Systematic Name

English

2(1H)-QUINOLINONE

Systematic Name

English

O-AMINOCINNAMIC ACID LACTAM

Common Name

English

2-HYDROXYQUINOLINE

Systematic Name

English

CARBOSTYRIL [MI]

Common Name

English

HYDROXYQUINOLINE, 2-

Systematic Name

English

Code System Code Type Description

CHEBI

18289