TRELOXINATE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C16H12Cl2O4
Molecular Weight	339.17
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC(=O)C1OC2=C(CC3=C(O1)C=CC(Cl)=C3)C=C(Cl)C=C2

InChI

InChIKey=BORQIQWYKSNHKN-UHFFFAOYSA-N

InChI=1S/C16H12Cl2O4/c1-20-15(19)16-21-13-4-2-11(17)7-9(13)6-10-8-12(18)3-5-14(10)22-16/h2-5,7-8,16H,6H2,1H3

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4635973 | Elks, J. (2014) The Dictionary of Drugs: Chemical Data, page 1225, retrieved from: https://books.google.ru/books?id=0vXTBwAAQBAJ | Bencze, W.L. et al. (2012) Hypolipidemic Agents, page 389, retrieved from: https://books.google.ru/books?id=a1bmCAAAQBAJ

Treloxinate is a potent hypolipidemic agent. Treloxinate and its acid are structurally related to clofibrate. The activities of treloxinate and its acid form have been found to be identical. In rats treloxinate is 8 times as potent as clofibrate in reducing plasma cholesterol levels and 30 times as potent in lowering plasma triglyceride concentration.

Approval Year

PubMed

Title	Date	PubMed
Treloxinate and related hypolipidemic 12H-dibenzo(d,g)(1,3)dioxocin-6-carboxylate derivatives.	1972 Dec	4635973

Name

Type

Language

TRELOXINATE

Official Name

English

treloxinate [INN]

Common Name

English

Methyl 2,10-dichloro-12H-dibenzo[d,g][1,3]dioxocin-6-carboxylate

Systematic Name

English

TRELOXINATE [USAN]

Common Name

English

NSC-162487

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C29703