1,4-BUTANEDIOL

Details

Stereochemistry	ACHIRAL
Molecular Formula	C4H10O2
Molecular Weight	90.121
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OCCCCO

InChI

InChIKey=WERYXYBDKMZEQL-UHFFFAOYSA-N

InChI=1S/C4H10O2/c5-3-1-2-4-6/h5-6H,1-4H2

HIDE SMILES / InChI

Approval Year

PubMed

Title	Date	PubMed
Toxicity and biodegradation of products from polyester hydrolysis.	2001	11413830
Gamma-hydroxybutyrate, gamma-butyrolactone, and 1,4-butanediol.	2001 Aug	11493842
Biodegradation of aliphatic-aromatic copolyesters: evaluation of the final biodegradability and ecotoxicological impact of degradation intermediates.	2001 Jul	11444312
A case of withdrawal from the GHB precursors gamma-butyrolactone and 1,4-butanediol.	2001 Jul	11399385
Convenient synthesis of aliphatic polyesters by distannoxane-catalyzed polycondensation.	2001 Winter	11777402
Treatment of a 1,4-butanediol poisoning with fomepizole.	2002	11990207
Central effects of 1,4-butanediol are mediated by GABA(B) receptors via its conversion into gamma-hydroxybutyric acid.	2002 Apr 26	12063087
Capillary gas chromatographic determination of 1,4-butanediol and gamma-hydroxybutyrate in human plasma and urine.	2002 Apr 5	11996487
Simultaneous analysis of gamma-hydroxybutyric acid, gamma-butyrolactone, and 1,4-butanediol by micellar electrokinetic chromatography.	2002 Feb 18	11909651
A novel route for synthesis of gamma-butyrolactone through the coupling of hydrogenation and dehydrogenation.	2002 Feb 7	12120391
Gamma hydroxybutyric acid (GHB) intoxication.	2002 Jul	12093716
Crystallization of the FAD-independent acetolactate synthase of Klebsiella pneumoniae.	2002 Jul	12077455
Pretreatment of CD-1 mice with 4-methylpyrazole blocks toxicity from the gamma-hydroxybutyrate precursor, 1,4-butanediol.	2002 Jul 5	12074936
WBC filtration of whole blood after prolonged storage at ambient temperature by use of an in-line filter collection system.	2002 Jun	12147026
Enzyme and receptor antagonists for preventing toxicity from the gamma-hydroxybutyric acid precursor 1,4-butanediol in CD-1 mice.	2002 Jun	12105121
A simple GC method for determination of cryoprotector diols 1,4-butanediol or 2,3-butanediol in isolated rat hepatocytes.	2002 Mar-Apr	12050779
Recovery of small bioparticles by interfacial partitioning.	2002 May 20	11948442
Human macrophage-mediated biodegradation of polyurethanes: assessment of candidate enzyme activities.	2002 Oct	12162329
Synthesis of double-headed 2-5A-antisense chimeras and their ability to activate human RNase L.	2003 Nov 17	14592484
Syntheses and physical characterization of new aliphatic triblock poly(L-lactide-b-butylene succinate-b-L-lactide)s bearing soft and hard biodegradable building blocks.	2003 Nov-Dec	14606915
New Zealand's first fatality linked to use of 1,4-butanediol (1,4-B, Fantasy): no evidence of coingestion or comorbidity.	2003 Oct 24	14583808
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 30-2003. A 21-year-old man with sudden alteration of mental status.	2003 Sep 25	14507952
Gamma-hydroxybutyrate: bridging the clinical-analytical gap.	2004	15298491
Gamma-butyrolactone and 1,4-butanediol: abused analogues of gamma-hydroxybutyrate.	2004	15298490
The inkjet cleaner "Hurricane"--another GhB recipe.	2004 Dec	15587253
Comparison of monolithic silica and polymethacrylate capillary columns for LC.	2004 Jul	15354556
Discriminative stimulus effects of gamma-hydroxybutyrate in pigeons: role of diazepam-sensitive and -insensitive GABA(A) and GABA(B) receptors.	2004 Mar	14718595
Simultaneous analysis of gamma-hydroxybutyric acid and its precursors in urine using liquid chromatography-tandem mass spectrometry.	2004 Nov 12	15595536
Adsorption of naphthalene on zeolite from aqueous solution.	2004 Sep 1	15276034
Optimization of binary porogen solvent composition for preparation of butyl methacrylate monoliths in capillary liquid chromatography.	2004 Sep 17	15499916

Patents

Name

Type

Language

1,4-BUTANEDIOL

Official Name

English

1,4-BUTANEDIOL [MI]

Common Name

English

NSC-406696

Code

English

1,4-BUTANEDIOL [HSDB]

Common Name

English

1,4-BUTYLENE GLYCOL

Systematic Name

English

1,4-TETRAMETHYLENE GLYCOL

Common Name

English

BUTANE-1,4-DIOL

Systematic Name

English

TETRAMETHYLENE GLYCOL

Systematic Name

English

1,4-BUTANEDIOL [INCI]

Common Name

English

1,4-DIHYDROXYBUTANE

Systematic Name

English

Classification Tree Code System Code

WIKIPEDIA

Designer-drugs-1,4-Butanediol