TOMINERSEN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Investigational

Investigational

Approval Year

Name

Type

Language

DNA, D((2'-O-(2-METHOXYETHYL))M5RC-SP-(2'-O-(2-METHOXYETHYL))M5RU-(2'-O-(2-METHOXYETHYL))M5RC-(2'-O-(2-METHOXYETHYL))RA-(2'-O-(2-METHOXYETHYL))RG-SP-T-SP-A-SP-A-SP-M5C-SP-A-SP-T-SP-T-SP-G-SP-A-SP-M5C-SP-(2'-O-(2-METHOXYETHYL))RA-(2'-O-(2-METHOXYETHYL))M5

Preferred Name

English

TOMINERSEN

Official Name

English

tominersen [INN]

Common Name

English

ISIS-443139 FREE ACID

Code

English

Tominersen [WHO-DD]

Common Name

English

RG-6042 FREE ACID

Code

English

RG6042 FREE ACID

Code

English

TOMINERSEN [USAN]

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

499215

Created by admin on Tue Apr 01 23:00:55 GMT 2025 , Edited by admin on Tue Apr 01 23:00:55 GMT 2025

Code System Code Type Description

FDA UNII

7QI41X9QWC

Created by admin on Tue Apr 01 23:00:55 GMT 2025 , Edited by admin on Tue Apr 01 23:00:55 GMT 2025

PRIMARY

SMS_ID

100000183660

Created by admin on Tue Apr 01 23:00:55 GMT 2025 , Edited by admin on Tue Apr 01 23:00:55 GMT 2025

PRIMARY

NCI_THESAURUS

C171741

Created by admin on Tue Apr 01 23:00:55 GMT 2025 , Edited by admin on Tue Apr 01 23:00:55 GMT 2025

PRIMARY

CAS

1709886-74-7

Created by admin on Tue Apr 01 23:00:55 GMT 2025 , Edited by admin on Tue Apr 01 23:00:55 GMT 2025

PRIMARY

INN

11052

Created by admin on Tue Apr 01 23:00:55 GMT 2025 , Edited by admin on Tue Apr 01 23:00:55 GMT 2025

PRIMARY

USAN

HI-118

Created by admin on Tue Apr 01 23:00:55 GMT 2025 , Edited by admin on Tue Apr 01 23:00:55 GMT 2025

PRIMARY

Sugar	Site Range	Site Count
Deoxyribose (DNA)	1_6-1_15	10 / 20
2'-O-Methoxyethyl ribose	1_1-1_5;1_16-1_20	10 / 20

Linkage	Site Range	Site Count
Phosporothioate	1_2;1_6-1_17;1_20	14 / 19
Phosphate	1_3-1_5;1_18-1_19	5 / 19

ACTIVE MOIETY


					7QI41X9QWC

SALT/SOLVATE (PARENT)


					5EO3CIJ3H7

TOMINERSEN SODIUM