NORDIHYDROGUAIARETIC ACID, (±)-

C[C@@H](CC1=CC(O)=C(O)C=C1)[C@@H](C)CC2=CC=C(O)C(O)=C2

InChIKey=HCZKYJDFEPMADG-RYUDHWBXSA-N

InChI=1S/C18H22O4/c1-11(7-13-3-5-15(19)17(21)9-13)12(2)8-14-4-6-16(20)18(22)10-14/h3-6,9-12,19-22H,7-8H2,1-2H3/t11-,12-/m0/s1

Targets

Primary Target	Pharmacology	Potency
Arachidonate 5-lipoxygenase 49 Target ID: CHEMBL215 Sources: https://www.ncbi.nlm.nih.gov/pubmed/21958737	Inhibitor 8297	25.0 nM [IC50]
Cytosolic phospholipase A2 7 Target ID: CHEMBL3816 Sources: https://www.ncbi.nlm.nih.gov/pubmed/3972457	Inhibitor 8297	13.0 µM [IC50]
Leukotriene B4 receptor 1 4 Target ID: CHEMBL3911 Sources: https://www.ncbi.nlm.nih.gov/pubmed/2825484 \| https://www.ncbi.nlm.nih.gov/pubmed/1313879	Antagonist 2778	50.0 µM [IC50]

Name

Type

Language

NORDIHYDROGUAIARETIC ACID, (±)-

Common Name

English

1,2-BENZENEDIOL, 4,4'-(2,3-DIMETHYL-1,4-BUTANEDIYL)BIS-, (R*,R*)-

Systematic Name

English

NORDIHYDROGUAIARETIC ACID, DL-

Common Name

English

1,2-BENZENEDIOL, 4,4'-((2R,3R)-2,3-DIMETHYL-1,4-BUTANEDIYL)BIS-, REL-

Systematic Name

English

Code System Code Type Description

DAILYMED

7PZ73W4ZNR