Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C18H22O6 |
| Molecular Weight | 334.3637 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=CC=C(C[C@@H](O)C2=CC(OC)=C(OC)C(OC)=C2)C=C1O
InChI
InChIKey=LGZKGOGODCLQHG-CYBMUJFWSA-N
InChI=1S/C18H22O6/c1-21-15-6-5-11(8-14(15)20)7-13(19)12-9-16(22-2)18(24-4)17(10-12)23-3/h5-6,8-10,13,19-20H,7H2,1-4H3/t13-/m1/s1
DescriptionCurator's Comment: Note: most of the information on combretastatin is in fact related to a combretastatin analog Combretastatin A4
Curator's Comment: Note: most of the information on combretastatin is in fact related to a combretastatin analog Combretastatin A4
Combretastatin is a phenol derivative isolated from the bark of Combretum caffrum, commonly known as South African Bush Willow. Combretastatin is an effective antimitotic agent, and like colchicine, inhibited tubulin polymerization and stimulated tubulin-dependent GTP hydrolysis.
Approval Year
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NCI_THESAURUS |
C67421
Created by
admin on Fri Dec 15 18:11:55 GMT 2023 , Edited by admin on Fri Dec 15 18:11:55 GMT 2023
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100000089840
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DTXSID80897571
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DB12596
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Combretastatin
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SUB26305
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9895264
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7O62J06F18
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C80014
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C040105
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82855-09-2
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348103
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m3747
Created by
admin on Fri Dec 15 18:11:55 GMT 2023 , Edited by admin on Fri Dec 15 18:11:55 GMT 2023
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PRIMARY | Merck Index |
SUBSTANCE RECORD
