Details
Stereochemistry | ACHIRAL |
Molecular Formula | 3Al.Na.2HO4P.4H2O.6H2O4P |
Molecular Weight | 949.8776 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
O.O.O.O.[Na+].[Al+3].[Al+3].[Al+3].OP(O)([O-])=O.OP(O)([O-])=O.OP(O)([O-])=O.OP(O)([O-])=O.OP(O)([O-])=O.OP(O)([O-])=O.OP([O-])([O-])=O.OP([O-])([O-])=O
InChI
InChIKey=IQQWMJSNEUUJAY-UHFFFAOYSA-D
InChI=1S/3Al.Na.8H3O4P.4H2O/c;;;;8*1-5(2,3)4;;;;/h;;;;8*(H3,1,2,3,4);4*1H2/q3*+3;+1;;;;;;;;;;;;/p-10
CNS Activity
Sources: https://www.ncbi.nlm.nih.gov/pubmed/24202578
Curator's Comment: Aluminum can be detected in the brain of Kasal treated dogs.
Approval Year
PubMed
Title | Date | PubMed |
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Toxicity and aluminium concentration in bone following dietary administration of two sodium aluminium phosphate formulations in rats. | 1987 Jul |
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Twenty-six week toxicity study with KASAL® (basic sodium aluminum phosphate) in beagle dogs. | 1990 Mar |
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Aluminum hydroxide adjuvants activate caspase-1 and induce IL-1beta and IL-18 release. | 2007 Apr 15 |
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Classification Tree | Code System | Code | ||
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CODEX ALIMENTARIUS (GSFA) |
INS-541(I)
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JECFA EVALUATION |
INS-541(I)
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72941495
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DTXSID80872525
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SODIUM ALUMINIUM PHOSPHATE
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PRIMARY | In addition to the usual hydrate, an anhydrous SAlP is also known, Na3H15Al2(PO4)8 (CAS#10279-59-1), referred to as 8:2:3, reflecting the ratio of phosphate to aluminium to sodium. Additionally an SAlP of ill-defined stoichiometry is used (NaxAly(PO4)z (CAS# 7785-88-8).[3] | ||
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7785-88-8
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NON-SPECIFIC STOICHIOMETRY | |||
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10305-76-7
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7N091Y877O
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232-090-4
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SUBSTANCE RECORD