Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C35H47N5O6 |
| Molecular Weight | 633.7776 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC1=CC(C[C@@H](OC(=O)N2CCC(CC2)N3CCC4=CC=CC=C4NC3=O)C(=O)N5CCC(CC5)N6CCOCC6)=CC(C)=C1O
InChI
InChIKey=HTLWMOKBJQKDIJ-WJOKGBTCSA-N
InChI=1S/C35H47N5O6/c1-24-21-26(22-25(2)32(24)41)23-31(33(42)38-12-8-28(9-13-38)37-17-19-45-20-18-37)46-35(44)39-14-10-29(11-15-39)40-16-7-27-5-3-4-6-30(27)36-34(40)43/h3-6,21-22,28-29,31,41H,7-20,23H2,1-2H3,(H,36,43)/t31-/m1/s1
Originator
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Review of dose-response curves for acute antimigraine drugs: triptans, 5-HT1F agonists and CGRP antagonists. | 2015 |
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| New Agents for Acute Treatment of Migraine: CGRP Receptor Antagonists, iNOS Inhibitors. | 2012-02 |
|
| Calcitonin gene-related peptide (CGRP) receptor antagonists in the treatment of migraine. | 2010-07 |
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| Code System | Code | Type | Description | ||
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866086-05-7
Created by
admin on Mon Mar 31 23:46:09 GMT 2025 , Edited by admin on Mon Mar 31 23:46:09 GMT 2025
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PRIMARY | |||
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23654987
Created by
admin on Mon Mar 31 23:46:09 GMT 2025 , Edited by admin on Mon Mar 31 23:46:09 GMT 2025
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PRIMARY | |||
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BI-44370
Created by
admin on Mon Mar 31 23:46:09 GMT 2025 , Edited by admin on Mon Mar 31 23:46:09 GMT 2025
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PRIMARY | Official Title: A Randomised, Double-blind, Placebo- and Active Comparator-controlled, Five Parallel Groups Study to Investigate the Efficacy and Safety of BI 44370 TA (50 mg, 200 mg, and 400 mg) Administered Orally Once During an Acute Migraine Attack of Moderate or Severe IntensityPurpose: The objective of this trial is to assess the safety, tolerability, and efficacy of three doses of BI 44370 TA in the treatment of patients with an acute migraine attack and headache pain of moderate or severe intensity, compared to placebo and an active comparator. | ||
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7L3WOA232W
Created by
admin on Mon Mar 31 23:46:09 GMT 2025 , Edited by admin on Mon Mar 31 23:46:09 GMT 2025
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PRIMARY |
ACTIVE MOIETY
