Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C22H22Cl2F3NO |
| Molecular Weight | 444.317 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCCCNCCC(O)C1=CC2=C(Cl)C=C(Cl)C=C2C3=CC(=CC=C13)C(F)(F)F
InChI
InChIKey=FYHCHSNOXWVJJT-UHFFFAOYSA-N
InChI=1S/C22H22Cl2F3NO/c1-2-3-7-28-8-6-21(29)19-12-18-17(10-14(23)11-20(18)24)16-9-13(22(25,26)27)4-5-15(16)19/h4-5,9-12,21,28-29H,2-3,6-8H2,1H3
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| The anti-malarial drug halofantrine and its metabolite N-desbutylhalofantrine block HERG potassium channels. | 2002 Sep |
|
| Desbutylhalofantrine: evaluation of QT prolongation and other cardiovascular effects after intravenous administration in vivo. | 2003 Mar |
|
| Effects of prior administration of amodiaquine on the disposition of halofantrine in healthy volunteers. | 2007 Apr |
|
| Effect of kolanut on the pharmacokinetics of the antimalarial drug halofantrine. | 2008 Jan |
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69756-48-5
Created by
admin on Sat Dec 16 08:03:41 GMT 2023 , Edited by admin on Sat Dec 16 08:03:41 GMT 2023
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7K35DDV85X
Created by
admin on Sat Dec 16 08:03:41 GMT 2023 , Edited by admin on Sat Dec 16 08:03:41 GMT 2023
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115076
Created by
admin on Sat Dec 16 08:03:41 GMT 2023 , Edited by admin on Sat Dec 16 08:03:41 GMT 2023
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DTXSID40989921
Created by
admin on Sat Dec 16 08:03:41 GMT 2023 , Edited by admin on Sat Dec 16 08:03:41 GMT 2023
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ACTIVE MOIETY
PARENT (METABOLITE ACTIVE)
