Details
Stereochemistry | ACHIRAL |
Molecular Formula | C10H13N5O |
Molecular Weight | 219.2431 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 1 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
C\C(CO)=C/CNC1=NC=NC2=C1N=CN2
InChI
InChIKey=UZKQTCBAMSWPJD-FARCUNLSSA-N
InChI=1S/C10H13N5O/c1-7(4-16)2-3-11-9-8-10(13-5-12-8)15-6-14-9/h2,5-6,16H,3-4H2,1H3,(H2,11,12,13,14,15)/b7-2+
DescriptionSources: https://www.ncbi.nlm.nih.gov/pubmed/15798374
Sources: https://www.ncbi.nlm.nih.gov/pubmed/15798374
Zeatin is a cytokinin plant growth factor, which has gerontomodulatory, youth preserving and anti-aging effects on serially passaged human adult skin fibroblasts undergoing aging in vitro.
Approval Year
Sample Use Guides
In Vitro Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/15798374
Zeatin has gerontomodulatory, youth preserving and anti-aging effects on serially passaged human adult skin fibroblasts undergoing aging in vitro. There were no immediate negative or toxic effects in terms of cell attachment, cell proliferation, cell survival, cytoskeletal organization, and cellular growth by treatment with zeatin concentrations between 1 and 200 microM. During long-term treatment, cells could be maintained throughout their replicative lifespan in the presence of 40, 80, and 200 microM zeatin, but the optimal concentration of zeatin's anti-aging and youth-preserving effects was found to be 80 microM.
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ZEATIN
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DB11337
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7I6OOJ9GR6
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m11585
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449093
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7I6OOJ9GR6
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15333
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DTXSID9040631
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1637-39-4
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zeatin
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ACTIVE MOIETY