Details
Stereochemistry | ACHIRAL |
Molecular Formula | C15H28O7P2 |
Molecular Weight | 382.3261 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 2 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(C)=CCC\C(C)=C\CC\C(C)=C\COP(O)(=O)OP(O)(O)=O
InChI
InChIKey=VWFJDQUYCIWHTN-YFVJMOTDSA-N
InChI=1S/C15H28O7P2/c1-13(2)7-5-8-14(3)9-6-10-15(4)11-12-21-24(19,20)22-23(16,17)18/h7,9,11H,5-6,8,10,12H2,1-4H3,(H,19,20)(H2,16,17,18)/b14-9+,15-11+
Approval Year
PubMed
Title | Date | PubMed |
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Natural and synthetic non-peptide antigens recognized by human gamma delta T cells. | 1995 May 11 |
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Post-translational regulation of mevalonate kinase by intermediates of the cholesterol and nonsterol isoprene biosynthetic pathways. | 1997 Nov |
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Determination of farnesyl pyrophosphate in dog and human plasma by high-performance liquid chromatography with fluorescence detection. | 1997 Oct 1 |
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Truncation of human squalene synthase yields active, crystallizable protein. | 1998 Feb 15 |
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The basis for K-Ras4B binding specificity to protein farnesyltransferase revealed by 2 A resolution ternary complex structures. | 2000 Feb 15 |
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Simvastatin modulates cytokine-mediated endothelial cell adhesion molecule induction: involvement of an inhibitory G protein. | 2000 Sep 1 |
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Tissue-specific transcriptional regulation of the cholesterol biosynthetic pathway leads to accumulation of testis meiosis-activating sterol (T-MAS). | 2002 Jan |
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A quantitative structure-activity relationship and pharmacophore modeling investigation of aryl-X and heterocyclic bisphosphonates as bone resorption agents. | 2003 Jul 3 |
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Transcriptional regulation of farnesyl pyrophosphate synthase by liver X receptors. | 2003 Sep |
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Substrate binding mode and reaction mechanism of undecaprenyl pyrophosphate synthase deduced from crystallographic studies. | 2004 Apr |
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Differential effects of simvastatin on mesangial cells. | 2004 Jul |
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Lysine beta311 of protein geranylgeranyltransferase type I partially replaces magnesium. | 2004 Jul 16 |
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Simvastatin augments lipopolysaccharide-induced proinflammatory responses in macrophages by differential regulation of the c-Fos and c-Jun transcription factors. | 2004 Jun 15 |
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Effect of pitavastatin on transactivation of human serum paraoxonase 1 gene. | 2005 Feb |
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Simvastatin inhibits central sympathetic outflow in heart failure by a nitric-oxide synthase mechanism. | 2008 Jul |
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Simvastatin antagonizes tumor necrosis factor-alpha inhibition of bone morphogenetic proteins-2-induced osteoblast differentiation by regulating Smad signaling and Ras/Rho-mitogen-activated protein kinase pathway. | 2008 Mar |
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Isopentenyl pyrophosphate is a novel antinociceptive substance that inhibits TRPV3 and TRPA1 ion channels. | 2011 May |
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17407
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DTXSID10864352
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DB07780
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FARNESYL PYROPHOSPHATE
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50277
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79W6B01D07
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13058-04-3
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445713
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SUBSTANCE RECORD