U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C15H28O7P2
Molecular Weight 382.3261
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 2
Charge 0

SHOW SMILES / InChI
Structure of FARNESYL PYROPHOSPHATE

SMILES

CC(C)=CCC\C(C)=C\CC\C(C)=C\COP(O)(=O)OP(O)(O)=O

InChI

InChIKey=VWFJDQUYCIWHTN-YFVJMOTDSA-N
InChI=1S/C15H28O7P2/c1-13(2)7-5-8-14(3)9-6-10-15(4)11-12-21-24(19,20)22-23(16,17)18/h7,9,11H,5-6,8,10,12H2,1-4H3,(H,19,20)(H2,16,17,18)/b14-9+,15-11+

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Natural and synthetic non-peptide antigens recognized by human gamma delta T cells.
1995 May 11
Post-translational regulation of mevalonate kinase by intermediates of the cholesterol and nonsterol isoprene biosynthetic pathways.
1997 Nov
Determination of farnesyl pyrophosphate in dog and human plasma by high-performance liquid chromatography with fluorescence detection.
1997 Oct 1
Truncation of human squalene synthase yields active, crystallizable protein.
1998 Feb 15
The basis for K-Ras4B binding specificity to protein farnesyltransferase revealed by 2 A resolution ternary complex structures.
2000 Feb 15
Simvastatin modulates cytokine-mediated endothelial cell adhesion molecule induction: involvement of an inhibitory G protein.
2000 Sep 1
Tissue-specific transcriptional regulation of the cholesterol biosynthetic pathway leads to accumulation of testis meiosis-activating sterol (T-MAS).
2002 Jan
A quantitative structure-activity relationship and pharmacophore modeling investigation of aryl-X and heterocyclic bisphosphonates as bone resorption agents.
2003 Jul 3
Transcriptional regulation of farnesyl pyrophosphate synthase by liver X receptors.
2003 Sep
Substrate binding mode and reaction mechanism of undecaprenyl pyrophosphate synthase deduced from crystallographic studies.
2004 Apr
Differential effects of simvastatin on mesangial cells.
2004 Jul
Lysine beta311 of protein geranylgeranyltransferase type I partially replaces magnesium.
2004 Jul 16
Simvastatin augments lipopolysaccharide-induced proinflammatory responses in macrophages by differential regulation of the c-Fos and c-Jun transcription factors.
2004 Jun 15
Effect of pitavastatin on transactivation of human serum paraoxonase 1 gene.
2005 Feb
Simvastatin inhibits central sympathetic outflow in heart failure by a nitric-oxide synthase mechanism.
2008 Jul
Simvastatin antagonizes tumor necrosis factor-alpha inhibition of bone morphogenetic proteins-2-induced osteoblast differentiation by regulating Smad signaling and Ras/Rho-mitogen-activated protein kinase pathway.
2008 Mar
Isopentenyl pyrophosphate is a novel antinociceptive substance that inhibits TRPV3 and TRPA1 ion channels.
2011 May
Name Type Language
FARNESYL PYROPHOSPHATE
Systematic Name English
FARNESYL DIPHOSPHATE
Systematic Name English
Code System Code Type Description
CHEBI
17407
Created by admin on Fri Dec 15 19:44:20 GMT 2023 , Edited by admin on Fri Dec 15 19:44:20 GMT 2023
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EPA CompTox
DTXSID10864352
Created by admin on Fri Dec 15 19:44:20 GMT 2023 , Edited by admin on Fri Dec 15 19:44:20 GMT 2023
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DRUG BANK
DB07780
Created by admin on Fri Dec 15 19:44:20 GMT 2023 , Edited by admin on Fri Dec 15 19:44:20 GMT 2023
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WIKIPEDIA
FARNESYL PYROPHOSPHATE
Created by admin on Fri Dec 15 19:44:20 GMT 2023 , Edited by admin on Fri Dec 15 19:44:20 GMT 2023
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CHEBI
50277
Created by admin on Fri Dec 15 19:44:20 GMT 2023 , Edited by admin on Fri Dec 15 19:44:20 GMT 2023
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FDA UNII
79W6B01D07
Created by admin on Fri Dec 15 19:44:20 GMT 2023 , Edited by admin on Fri Dec 15 19:44:20 GMT 2023
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CAS
13058-04-3
Created by admin on Fri Dec 15 19:44:20 GMT 2023 , Edited by admin on Fri Dec 15 19:44:20 GMT 2023
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PUBCHEM
445713
Created by admin on Fri Dec 15 19:44:20 GMT 2023 , Edited by admin on Fri Dec 15 19:44:20 GMT 2023
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