METABISULFITE ION

Details

Stereochemistry	ACHIRAL
Molecular Formula	O5S2
Molecular Weight	144.127
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	-2

SHOW SMILES / InChI

Structure Search

SMILES

[O-]S(=O)S([O-])(=O)=O

InChI

InChIKey=WBZKQQHYRPRKNJ-UHFFFAOYSA-L

InChI=1S/H2O5S2/c1-6(2)7(3,4)5/h(H,1,2)(H,3,4,5)/p-2

HIDE SMILES / InChI

Description
Sources: https://www.food.gov.uk/business-guidance/eu-approved-additives-and-e-numbers | https://www.ncbi.nlm.nih.gov/pubmed/30031916

METABISULFITE ION is a food additive, also known as E-224. It is used as the preservative in processed fruit products including dried fruits, juices, and wine.

Approval Year

PubMed

Title	Date	PubMed
Preservation of fruit and vegetable discards with sodium metabisulfite.	2018-10-15	30031916
Effects of sodium metabisulfite on the expression of BK(Ca), K(ATP), and L-Ca(2+) channels in rat aortas in vivo and in vitro.	2015-03-02	25463229

Sample Use Guides

In Vitro Use Guide

The purpose of the study was to investigate the effect of sodium metabisulfite (SMB) on the expression of big-conductance Ca(2+)-activated K(+) (BKCa), ATP-sensitive K(+) (KATP), and L-type calcium (L-Ca(2+)) channels in rat aorta in vivo and in vitro. The results showed that the mRNA and protein levels of the BKCa channel subunits α and β1 of the aorta in rats were increased by SMB in vivo and in vitro. Similarly, the expression of the KATP channel subunits Kir6.1, Kir6.2, and SUR2B were increased by SMB. However, SMB at the highest concentration significantly decreased the expression of the L-Ca(2+) channel subunits Cav1.2 and Cav1.3.

Name

Type

Language

METABISULFITE ION

Common Name

English

DISULFITE (S2O52-)

Preferred Name

English

PYROSULFITE

Systematic Name

English

METABISULFITE

Systematic Name

English

DISULFITE

Systematic Name

English

DISULFITE ION

Common Name

English

DISULFUROUS ACID, ION(2-)

Common Name

English

PYROSULFITE (S2O52-)

Common Name

English

METASULFITE (S2O52-)

Common Name

English

Code System Code Type Description

CHEBI

29251