ATORVASTATIN LACTONE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C33H33FN2O4
Molecular Weight	540.6245
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)C1=C(C(=O)NC2=CC=CC=C2)C(=C(N1CC[C@@H]3C[C@@H](O)CC(=O)O3)C4=CC=C(F)C=C4)C5=CC=CC=C5

InChI

InChIKey=OUCSEDFVYPBLLF-KAYWLYCHSA-N

InChI=1S/C33H33FN2O4/c1-21(2)31-30(33(39)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-27-19-26(37)20-28(38)40-27/h3-16,21,26-27,37H,17-20H2,1-2H3,(H,35,39)/t26-,27-/m1/s1

HIDE SMILES / InChI

Approval Year

PubMed

Title	Date	PubMed
Evaluation of the anti-HIV activity of statins.	2005-10-14	16184043
Inhibitors of cholesterol biosynthesis. 3. Tetrahydro-4-hydroxy-6-[2-(1H-pyrrol-1-yl)ethyl]-2H-pyran-2-one inhibitors of HMG-CoA reductase. 2. Effects of introducing substituents at positions three and four of the pyrrole nucleus.	1991-01	1992137

Patents

Name

Type

Language

ATORVASTATIN LACTONE

Common Name

English

(+)-ATORVASTATIN LACTONE

Preferred Name

English

ATORVASTATIN CALCIUM IMPURITY H [EP IMPURITY]

Common Name

English

1H-PYRROLE-3-CARBOXAMIDE, 5-(4-FLUOROPHENYL)-2-(1-METHYLETHYL)-N,4-DIPHENYL-1-(2-((2R,4R)-TETRAHYDRO-4-HYDROXY-6-OXO-2H-PYRAN-2-YL)ETHYL)-

Systematic Name

English

ATORVASTATIN RELATED COMPOUND H [USP IMPURITY]

Common Name

English

ATORVASTATIN RELATED COMPOUND H [USP-RS]

Common Name

English

ATORVASTATIN .DELTA.-LACTONE

Common Name

English

1H-PYRROLE-3-CARBOXAMIDE, 5-(4-FLUOROPHENYL)-2-(1-METHYLETHYL)-N,4-DIPHENYL-1-(2-(TETRAHYDRO-4-HYDROXY-6-OXO-2H-PYRAN-2-YL)ETHYL)-, (2R-TRANS)-

Common Name

English

5-(4-FLUOROPHENYL)-1-(2-((2R,4R)-4-HYDROXY-6-OXOTETRAHYDROPYRAN-2-YL)ETHYL)-2-ISOPROPYL-4-PHENYL-1H-PYRROLE-3-CARBOXYLIC ACID PHENYLAMIDE

Systematic Name

English

ATORVASTATIN LACTONE [MI]

Common Name

English

Code System Code Type Description

PUBCHEM

6483036