METIAPINE

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C19H21N3S
Molecular Weight	323.455
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of METIAPINE

Structure Search

SMILES

CN1CCN(CC1)C2=NC3=C(SC4=C2C=C(C)C=C4)C=CC=C3

InChI

InChIKey=IOEPXYJOHIZYGQ-UHFFFAOYSA-N

InChI=1S/C19H21N3S/c1-14-7-8-17-15(13-14)19(22-11-9-21(2)10-12-22)20-16-5-3-4-6-18(16)23-17/h3-8,13H,9-12H2,1-2H3

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4198309 | https://www.ncbi.nlm.nih.gov/pubmed/28349512

Metiapine, a dibenzothiazepine derivative, possesses neuroleptic and antipsychotic properties. This drug was developed for the treatment of schizophrenia. However, the further development of this drug was stopped because of the presence of more effective drugs.

Approval Year

PubMed

PubMed

Title	Date	PubMed

Sample Use Guides

In Vivo Use Guide

Metiapine: capsule, range 100 mg/day to 600 mg/day

Route of Administration: Oral

Name

Type

Language

METIAPINE

Official Name

English

DIBENZO(B,F)(1,4)THIAZEPINE, 2-METHYL-11-(4-METHYL-1-PIPERAZINYL)-

Systematic Name

English

metiapine [INN]

Common Name

English

METIAPINE [USAN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29710

Created by admin on Sat Dec 16 15:52:37 GMT 2023 , Edited by admin on Sat Dec 16 15:52:37 GMT 2023

Code System Code Type Description

ChEMBL

CHEMBL2106892

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EPA CompTox

DTXSID7020891

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SMS_ID

100000080892

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PUBCHEM

22047

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INN

2669

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MESH

C005179

Created by admin on Sat Dec 16 15:52:37 GMT 2023 , Edited by admin on Sat Dec 16 15:52:37 GMT 2023

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NCI_THESAURUS

C90761

Created by admin on Sat Dec 16 15:52:37 GMT 2023 , Edited by admin on Sat Dec 16 15:52:37 GMT 2023

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WIKIPEDIA

Metiapine

Created by admin on Sat Dec 16 15:52:37 GMT 2023 , Edited by admin on Sat Dec 16 15:52:37 GMT 2023

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FDA UNII

775D6D91J8

Created by admin on Sat Dec 16 15:52:37 GMT 2023 , Edited by admin on Sat Dec 16 15:52:37 GMT 2023

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CAS

5800-19-1

Created by admin on Sat Dec 16 15:52:37 GMT 2023 , Edited by admin on Sat Dec 16 15:52:37 GMT 2023

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EVMPD

SUB08882MIG

Created by admin on Sat Dec 16 15:52:37 GMT 2023 , Edited by admin on Sat Dec 16 15:52:37 GMT 2023

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ACTIVE MOIETY


					775D6D91J8

METIAPINE