Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C23H38N7O17P3S |
| Molecular Weight | 809.571 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 5 / 5 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N2C=NC3=C2N=CN=C3N
InChI
InChIKey=ZSLZBFCDCINBPY-ZSJPKINUSA-N
InChI=1S/C23H38N7O17P3S/c1-12(31)51-7-6-25-14(32)4-5-26-21(35)18(34)23(2,3)9-44-50(41,42)47-49(39,40)43-8-13-17(46-48(36,37)38)16(33)22(45-13)30-11-29-15-19(24)27-10-28-20(15)30/h10-11,13,16-18,22,33-34H,4-9H2,1-3H3,(H,25,32)(H,26,35)(H,39,40)(H,41,42)(H2,24,27,28)(H2,36,37,38)/t13-,16-,17-,18+,22-/m1/s1
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| 3-Hydroxy-3-methylglutaric aciduria, combined with 3-methylglutaconic aciduria. | 1976 Aug 2 |
|
| Acetyl group accumulation and pyruvate dehydrogenase activity in human muscle during incremental exercise. | 1991 Dec |
|
| Effects of fat on insulin-stimulated carbohydrate metabolism in normal men. | 1991 Sep |
|
| Viral infections: a role in the lung disease of cystic fibrosis? | 1992 Feb |
|
| Caffeine ingestion and muscle metabolism during prolonged exercise in humans. | 1992 Jun |
|
| Localization of carnitine acetyltransferase activity in brown adipocytes of the rat. | 1994 Apr |
|
| Human cytoplasmic 3-hydroxy-3-methylglutaryl coenzyme A synthase: expression, purification, and characterization of recombinant wild-type and Cys129 mutant enzymes. | 1994 Jul |
|
| The CoA-independent transacylase in PAF biosynthesis: tissue distribution and molecular species selectivity. | 1995 Feb 9 |
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| Skeletal muscle pyruvate dehydrogenase activity during acetate infusion in humans. | 1995 May |
|
| [Mechanisms of selective vulnerability of cholinergic neurons to neurotoxic stimuli]. | 1999 |
|
| Effects of acetate infusion and hyperoxia on muscle substrate phosphorylation after onset of moderate exercise. | 2001 Dec |
|
| Regulation of PDH activity and isoform expression: diet and exercise. | 2003 Dec |
|
| Acetylation regulates the differentiation-specific functions of the retinoblastoma protein. | 2004 Apr 7 |
|
| Muscle pyruvate availability can limit the flux, but not activation, of the pyruvate dehydrogenase complex during submaximal exercise in humans. | 2004 Dec 1 |
|
| Insulin regulation of fatty acid synthase gene transcription: roles of USF and SREBP-1c. | 2004 Oct |
|
| [Contribution of free fatty acids to impairment of insulin secretion and action. mechanism of beta-cell lipotoxicity]. | 2005 Dec |
|
| Phenotype dependent differential effects of interleukin-1beta and amyloid-beta on viability and cholinergic phenotype of T17 neuroblastoma cells. | 2005 Dec |
|
| N-Acetyltransferase and sulfotransferase activity in human prostate: potential for carcinogen activation. | 2006 Jun |
|
| Crystallographic and kinetic studies of human mitochondrial acetoacetyl-CoA thiolase: the importance of potassium and chloride ions for its structure and function. | 2007 Apr 10 |
|
| A visible wavelength spectrophotometric assay suitable for high-throughput screening of 3-hydroxy-3-methylglutaryl-CoA synthase. | 2010 Jan 1 |
Patents
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|---|---|---|---|---|
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| Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C384
Created by
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| Code System | Code | Type | Description | ||
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DTXSID30992686
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76Q83YLO3O
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C199
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72-89-9
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200-790-9
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76Q83YLO3O
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1490796
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Acetyl coenzyme A
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444493
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15351
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ACTIVE MOIETY
