Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C6H7O4P |
| Molecular Weight | 174.0911 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OP(O)(=O)OC1=CC=CC=C1
InChI
InChIKey=CMPQUABWPXYYSH-UHFFFAOYSA-N
InChI=1S/C6H7O4P/c7-11(8,9)10-6-4-2-1-3-5-6/h1-5H,(H2,7,8,9)
Disodium phenyl phosphate is a monophenyl ester of phosphoric acid. It is used as tool compound to study the efficacy of phosphatases. Hydrolysis of phenyl phosphate by milk phosphatases was used to used to indicate whether milk has been adequately pasteurized or whether it has been contaminated with raw milk after pasteurization. Phenyl phosphate was also used as a molecular fragment for fragment-based drug discovery of Src SH2.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Continuous assay for acid phosphatase using phenyl phosphate. | 1996 Oct 15 |
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| Cooperative kinetics of human prostatic acid phosphatase. | 2001 Aug 13 |
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| Purification and characterization of banana fruit acid phosphatase. | 2001 Dec |
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| Elaboration and characterization of spatially controlled assemblies of complementary polyphenol oxidase-alkaline phosphatase activities on electrodes. | 2001 Jul 1 |
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| Cloning and characterization of a second acid phosphatase from Sinorhizobium meliloti strain 104A14. | 2001 Oct |
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| Alkaline phosphatase revisited: hydrolysis of alkyl phosphates. | 2002 Mar 5 |
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| Effects of some trivalent metal ions on the fluoride-induced chemiluminescence from a phenylphosphate-substituted dioxetane Lumigen PPD. | 2002 Sep-Oct |
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| The yeast ISN1 (YOR155c) gene encodes a new type of IMP-specific 5'-nucleotidase. | 2003 May 7 |
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| Inhibitors for proteins endowed with catalytic and non-catalytic activity which recognize pTyr. | 2004 Oct |
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| Rapid and highly sensitive electrochemical determination of alkaline phosphatase using a composite tyrosinase biosensor. | 2005 Jan 15 |
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| An 18 kDa acid phosphatase from chicken heart possesses phosphotransferase activity. | 2006 Feb |
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| Theoretical evaluation of the substrate-assisted catalysis mechanism for the hydrolysis of phosphate monoester dianions. | 2007 |
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| Nanostructured progesterone immunosensor using a tyrosinase-colloidal gold-graphite-Teflon biosensor as amperometric transducer. | 2007 Jul 16 |
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| A highly sensitive assay for monitoring the secretory pathway and ER stress. | 2007 Jun 27 |
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| Time-resolved fluorescence-based assay for the determination of alkaline phosphatase activity and application to the screening of its inhibitors. | 2008 Jan |
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| A DFT study on the formation of a phosphohistidine intermediate in prostatic acid phosphatase. | 2008 Jul 30 |
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| [Comparative-enzymologic study of phosphatase activity of hydrobionts from Pacific Ocean]. | 2009 Jul-Aug |
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| Enhanced bactericidal activity of enterocin AS-48 in combination with essential oils, natural bioactive compounds and chemical preservatives against Listeria monocytogenes in ready-to-eat salad. | 2009 Sep |
|
| Delayed treatment with systemic (S)-roscovitine provides neuroprotection and inhibits in vivo CDK5 activity increase in animal stroke models. | 2010 Aug 12 |
|
| Immobilization of enzymes at high load/activity by aqueous electrodeposition of enzyme-tethered chitosan for highly sensitive amperometric biosensing. | 2010 Aug 15 |
|
| Expression and regulation of cyclic nucleotide phosphodiesterases in human and rat pancreatic islets. | 2010 Dec 1 |
|
| Chemoprotective Effect of Sobatum against Lithium-Induced Oxidative Damage in Rats. | 2010 Jan |
|
| Phosphoproteomics-based modeling defines the regulatory mechanism underlying aberrant EGFR signaling. | 2010 Nov 10 |
Sample Use Guides
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CFR |
21 CFR 176.170
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701-64-4
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75M88J863E
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DB03298
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DTXSID6044981
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12793
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211-857-7
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37548
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SUBSTANCE RECORD
