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Details

Stereochemistry ACHIRAL
Molecular Formula C6H7O4P
Molecular Weight 174.0911
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of MONOPHENYL PHOSPHATE

SMILES

OP(O)(=O)OC1=CC=CC=C1

InChI

InChIKey=CMPQUABWPXYYSH-UHFFFAOYSA-N
InChI=1S/C6H7O4P/c7-11(8,9)10-6-4-2-1-3-5-6/h1-5H,(H2,7,8,9)

HIDE SMILES / InChI

Description

Disodium phenyl phosphate is a monophenyl ester of phosphoric acid. It is used as tool compound to study the efficacy of phosphatases. Hydrolysis of phenyl phosphate by milk phosphatases was used to used to indicate whether milk has been adequately pasteurized or whether it has been contaminated with raw milk after pasteurization. Phenyl phosphate was also used as a molecular fragment for fragment-based drug discovery of Src SH2.

Originator

Approval Year

Conditions

ConditionModalityTargetsHighest PhaseProduct

PubMed

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
In kinetic studies, hydrolysis of phenyl phosphate by phosphatase was commenced by addition of enzyme solution to a buffered substrate and stopped by the addition of 20% trichloroacetic acid. Inorganic phosphate was estimated colorimetrically by the method of Fiske & Subbarow.