PF-06843195

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C20H25F3N8O4
Molecular Weight	498.4589
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC1=NC=C(C=N1)C2=NC(=NC(N[C@@]3(CO)CCN(C3)C(=O)OCC(F)F)=C2F)N4CCOCC4

InChI

InChIKey=RTOREZYNLPQUKM-FQEVSTJZSA-N

InChI=1S/C20H25F3N8O4/c21-13(22)9-35-19(33)31-2-1-20(10-31,11-32)29-16-14(23)15(12-7-25-17(24)26-8-12)27-18(28-16)30-3-5-34-6-4-30/h7-8,13,32H,1-6,9-11H2,(H2,24,25,26)(H,27,28,29)/t20-/m0/s1

HIDE SMILES / InChI

Approval Year

Name

Type

Language

PF-06843195

Code

English

1-PYRROLIDINECARBOXYLIC ACID, 3-((2'-AMINO-5-FLUORO-2-(4-MORPHOLINYL)(4,5'-BIPYRIMIDIN)-6-YL)AMINO)-3-(HYDROXYMETHYL)-, 2,2-DIFLUOROETHYL ESTER, (3S)-

Preferred Name

English

2,2-DIFLUOROETHYL (3S)-3-((2'-AMINO-5-FLUORO-2-(4-MORPHOLINYL)(4,5'-BIPYRIMIDIN)-6-YL)AMINO)-3-(HYDROXYMETHYL)-1-PYRROLIDINECARBOXYLATE

Systematic Name

English

2,2-DIFLUOROETHYL (3S)-3-((2'-AMINO-5-FLUORO-2-(MORPHOLIN-4-YL)-4,5'-BIPYRIMIDIN-6-YL)AMINO)-3-(HYDROXYMETHYL)PYRROLIDINE-1-CARBOXYLATE

Systematic Name

English

Code System Code Type Description

CAS

2067281-51-8

Created by admin on Wed Apr 02 12:44:02 GMT 2025 , Edited by admin on Wed Apr 02 12:44:02 GMT 2025

PRIMARY

FDA UNII

75658JDG29

Created by admin on Wed Apr 02 12:44:02 GMT 2025 , Edited by admin on Wed Apr 02 12:44:02 GMT 2025

PRIMARY

PUBCHEM

124193915

Created by admin on Wed Apr 02 12:44:02 GMT 2025 , Edited by admin on Wed Apr 02 12:44:02 GMT 2025

PRIMARY

ACTIVE MOIETY


					75658JDG29

PF-06843195

PRODRUG (METABOLITE ACTIVE)


					F92Z3RN37G

PF-06843195 PHOSPHATE ESTER