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Details

Stereochemistry ACHIRAL
Molecular Formula C32H37NO6
Molecular Weight 531.6393
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of GSK-376501

SMILES

COCCOC1=CC(OCCOC)=CC(CN2C3=C(C=CC=C3)C(=C2C(O)=O)C4=CC=C(C=C4)C(C)(C)C)=C1

InChI

InChIKey=OIDYMQICWGYEDR-UHFFFAOYSA-N
InChI=1S/C32H37NO6/c1-32(2,3)24-12-10-23(11-13-24)29-27-8-6-7-9-28(27)33(30(29)31(34)35)21-22-18-25(38-16-14-36-4)20-26(19-22)39-17-15-37-5/h6-13,18-20H,14-17,21H2,1-5H3,(H,34,35)

HIDE SMILES / InChI
GlaxoSmithKline was developing GSK-376501 as an oral peroxisome proliferator-activated receptor gamma partial agonist. This compound participated in phase I clinical trials for the treatment and diagnostic of patients with Type 2 Diabetes Mellitus, however, GSK discontinued the study of GSK-376501.

Approval Year

Sample Use Guides

Unknown
Route of Administration: Oral
Name Type Language
GSK-376501
Common Name English
GSK-376501A
Code English
GSK376501A
Code English
1H-INDOLE-2-CARBOXYLIC ACID, 1-((3,5-BIS(2-METHOXYETHOXY)PHENYL)METHYL)-3-(4-(1,1-DIMETHYLETHYL)PHENYL)-
Systematic Name English
GSK376501
Code English
Code System Code Type Description
DRUG BANK
DB12654
Created by admin on Sat Dec 16 08:51:38 GMT 2023 , Edited by admin on Sat Dec 16 08:51:38 GMT 2023
PRIMARY
PUBCHEM
24946920
Created by admin on Sat Dec 16 08:51:38 GMT 2023 , Edited by admin on Sat Dec 16 08:51:38 GMT 2023
PRIMARY
FDA UNII
7511RY999U
Created by admin on Sat Dec 16 08:51:38 GMT 2023 , Edited by admin on Sat Dec 16 08:51:38 GMT 2023
PRIMARY
CAS
1010412-80-2
Created by admin on Sat Dec 16 08:51:38 GMT 2023 , Edited by admin on Sat Dec 16 08:51:38 GMT 2023
PRIMARY