Details
Stereochemistry | ACHIRAL |
Molecular Formula | C2H3FO2 |
Molecular Weight | 77.045 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)C[18F]
InChI
InChIKey=QEWYKACRFQMRMB-KTXUZGJCSA-N
InChI=1S/C2H3FO2/c3-1-2(4)5/h1H2,(H,4,5)/i3-1
Fluoroacetic acid F-18 (18F-Fluoroacetate,18F-FAC) is an analog of acetate with a longer radioactive half-life (18F=110 min). Fluoroacetic acid F-18 was under investigation as a PET imaging agent. 18F-FAC was considered a promising alternative to 11C-ACE for positron tomographic imaging of prostate cancer, and possibly of other neoplasms with relatively low glucose use.
Approval Year
PubMed
Title | Date | PubMed |
---|---|---|
Long-chain F-18 fatty acids for the study of regional metabolism in heart and liver; odd-even effects of metabolism in mice. | 1979 Nov |
|
18F-fluoroacetate: a potential acetate analog for prostate tumor imaging--in vivo evaluation of 18F-fluoroacetate versus 11C-acetate. | 2007 Mar |
|
Evaluation of 6-([(18)F]fluoroacetamido)-1-hexanoicanilide for PET imaging of histone deacetylase in the baboon brain. | 2009 Apr |
Patents
Sample Use Guides
In Vivo Use Guide
Sources: https://clinicaltrials.gov/ct2/show/NCT01320787
Fluoroacetic acid F-18 (18F-fluoroacetate) injection as a single intravenous bolus with a maximum volume of 4 mL followed by a saline flush of 20 to 50 mL.
Route of Administration:
Intravenous
Name | Type | Language | ||
---|---|---|---|---|
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English |
Code System | Code | Type | Description | ||
---|---|---|---|---|---|
|
DTXSID20226624
Created by
admin on Sat Dec 16 02:14:07 GMT 2023 , Edited by admin on Sat Dec 16 02:14:07 GMT 2023
|
PRIMARY | |||
|
450656
Created by
admin on Sat Dec 16 02:14:07 GMT 2023 , Edited by admin on Sat Dec 16 02:14:07 GMT 2023
|
PRIMARY | |||
|
74Q3U8O789
Created by
admin on Sat Dec 16 02:14:07 GMT 2023 , Edited by admin on Sat Dec 16 02:14:07 GMT 2023
|
PRIMARY | |||
|
DB15202
Created by
admin on Sat Dec 16 02:14:07 GMT 2023 , Edited by admin on Sat Dec 16 02:14:07 GMT 2023
|
PRIMARY | |||
|
7574-44-9
Created by
admin on Sat Dec 16 02:14:07 GMT 2023 , Edited by admin on Sat Dec 16 02:14:07 GMT 2023
|
PRIMARY |
SALT/SOLVATE (PARENT)
SUBSTANCE RECORD