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Details

Stereochemistry ACHIRAL
Molecular Formula C2H3FO2
Molecular Weight 77.045
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FLUOROACETIC ACID F-18

SMILES

OC(=O)C[18F]

InChI

InChIKey=QEWYKACRFQMRMB-KTXUZGJCSA-N
InChI=1S/C2H3FO2/c3-1-2(4)5/h1H2,(H,4,5)/i3-1

HIDE SMILES / InChI
Fluoroacetic acid F-18 (18F-Fluoroacetate,18F-FAC) is an analog of acetate with a longer radioactive half-life (18F=110 min). Fluoroacetic acid F-18 was under investigation as a PET imaging agent. 18F-FAC was considered a promising alternative to 11C-ACE for positron tomographic imaging of prostate cancer, and possibly of other neoplasms with relatively low glucose use.

Approval Year

PubMed

PubMed

TitleDatePubMed
Long-chain F-18 fatty acids for the study of regional metabolism in heart and liver; odd-even effects of metabolism in mice.
1979 Nov
18F-fluoroacetate: a potential acetate analog for prostate tumor imaging--in vivo evaluation of 18F-fluoroacetate versus 11C-acetate.
2007 Mar
Evaluation of 6-([(18)F]fluoroacetamido)-1-hexanoicanilide for PET imaging of histone deacetylase in the baboon brain.
2009 Apr
Patents

Patents

Sample Use Guides

Fluoroacetic acid F-18 (18F-fluoroacetate) injection as a single intravenous bolus with a maximum volume of 4 mL followed by a saline flush of 20 to 50 mL.
Route of Administration: Intravenous
Name Type Language
FLUOROACETIC ACID F-18
Common Name English
18F-FLUOROACETATE
Common Name English
ACETIC ACID, FLUORO-18F-
Common Name English
Code System Code Type Description
EPA CompTox
DTXSID20226624
Created by admin on Sat Dec 16 02:14:07 GMT 2023 , Edited by admin on Sat Dec 16 02:14:07 GMT 2023
PRIMARY
PUBCHEM
450656
Created by admin on Sat Dec 16 02:14:07 GMT 2023 , Edited by admin on Sat Dec 16 02:14:07 GMT 2023
PRIMARY
FDA UNII
74Q3U8O789
Created by admin on Sat Dec 16 02:14:07 GMT 2023 , Edited by admin on Sat Dec 16 02:14:07 GMT 2023
PRIMARY
DRUG BANK
DB15202
Created by admin on Sat Dec 16 02:14:07 GMT 2023 , Edited by admin on Sat Dec 16 02:14:07 GMT 2023
PRIMARY
CAS
7574-44-9
Created by admin on Sat Dec 16 02:14:07 GMT 2023 , Edited by admin on Sat Dec 16 02:14:07 GMT 2023
PRIMARY