AZETIRELIN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Possibly Marketed Outside US

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C15H20N6O4
Molecular Weight	348.3571
Optical Activity	UNSPECIFIED
Defined Stereocenters	3 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of AZETIRELIN

Structure Search

SMILES

NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC2=CN=CN2)NC(=O)[C@@H]3CC(=O)N3

InChI

InChIKey=WBGUMUGCONUXFK-DCAQKATOSA-N

InChI=1S/C15H20N6O4/c16-13(23)11-2-1-3-21(11)15(25)10(4-8-6-17-7-18-8)20-14(24)9-5-12(22)19-9/h6-7,9-11H,1-5H2,(H2,16,23)(H,17,18)(H,19,22)(H,20,24)/t9-,10-,11-/m0/s1

HIDE SMILES / InChI

Description
Sources: https://adisinsight.springer.com/drugs/800002150 | https://www.ncbi.nlm.nih.gov/pubmed/10408236

Azetirelin (also known as YM-14673), a new thyroid-releasing hormone (TRH) analog, which was participated in clinical trials phase III in Japan for the treatment of cerebrovascular disorders and of neurological disorders.

Originator

Approval Year

Name

Type

Language

AZETIRELIN [JAN]

Preferred Name

English

AZETIRELIN

Official Name

English

azetirelin [INN]

Common Name

English

(-)-N-(((2S)-4-OXO-2-AZETIDINYL)CARBONYL)-L-HISTIDYL-L-PROLINAMIDE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C76367

Created by admin on Mon Mar 31 18:32:47 GMT 2025 , Edited by admin on Mon Mar 31 18:32:47 GMT 2025

Code System Code Type Description

MESH

C054995

Created by admin on Mon Mar 31 18:32:47 GMT 2025 , Edited by admin on Mon Mar 31 18:32:47 GMT 2025

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EVMPD

SUB05653MIG

Created by admin on Mon Mar 31 18:32:47 GMT 2025 , Edited by admin on Mon Mar 31 18:32:47 GMT 2025

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CAS

95729-65-0

Created by admin on Mon Mar 31 18:32:47 GMT 2025 , Edited by admin on Mon Mar 31 18:32:47 GMT 2025

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INN

6363

Created by admin on Mon Mar 31 18:32:47 GMT 2025 , Edited by admin on Mon Mar 31 18:32:47 GMT 2025

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SMS_ID

100000086102

Created by admin on Mon Mar 31 18:32:47 GMT 2025 , Edited by admin on Mon Mar 31 18:32:47 GMT 2025

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FDA UNII

70J5AWG54Q

Created by admin on Mon Mar 31 18:32:47 GMT 2025 , Edited by admin on Mon Mar 31 18:32:47 GMT 2025

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PUBCHEM

65841

Created by admin on Mon Mar 31 18:32:47 GMT 2025 , Edited by admin on Mon Mar 31 18:32:47 GMT 2025

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EPA CompTox

DTXSID20241938

Created by admin on Mon Mar 31 18:32:47 GMT 2025 , Edited by admin on Mon Mar 31 18:32:47 GMT 2025

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ChEMBL

CHEMBL2104559

Created by admin on Mon Mar 31 18:32:47 GMT 2025 , Edited by admin on Mon Mar 31 18:32:47 GMT 2025

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NCI_THESAURUS

C74408

Created by admin on Mon Mar 31 18:32:47 GMT 2025 , Edited by admin on Mon Mar 31 18:32:47 GMT 2025

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ACTIVE MOIETY


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