AGMATINE

Investigational

Details

Stereochemistry	ACHIRAL
Molecular Formula	C5H14N4
Molecular Weight	130.1915
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

SMILES

NCCCCNC(N)=N

InChI

InChIKey=QYPPJABKJHAVHS-UHFFFAOYSA-N

InChI=1S/C5H14N4/c6-3-1-2-4-9-5(7)8/h1-4,6H2,(H4,7,8,9)

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Approval Year

Targets

Targets

Primary Target	Pharmacology	Potency
Nitric-oxide synthase, brain 24	Inhibitor 8,504	660.0 µM [Ki]
Nitric oxide synthase, inducible 55	Inhibitor 8,504	220.0 µM [Ki]
Nitric-oxide synthase, endothelial 19	Inhibitor 8,504	7.5 mM [Ki]

PubMed

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Title	Date	PubMed
Polyamines of the thermophilic eubacteria belonging to the genera Thermosipho, Thermaerobacter and Caldicellulosiruptor.	2001	11327112
[Action of agmatine on tension of isolated aortic artery and its receptor mechanism in rats].	2001 Apr	11471213
The effect of agmatine administration on ischemic-reperfused isolated rat heart.	2001 Jan	11452335
Use of trifluoroperazine isolates a [(3)H]Ifenprodil binding site in rat brain membranes with the pharmacology of the voltage-independent ifenprodil site on N-methyl-D-aspartate receptors containing NR2B subunits.	2001 Jan	11123375
Agmatine uptake by cultured hamster kidney cells.	2001 Jan 12	11162515

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Patents

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Name

Type

Language

AGMATINE

Systematic Name

English

NSC-56332

Preferred Name

English

Agmatine [WHO-DD]

Common Name

English

1-AMINO-4-GUANIDOBUTANE

Common Name

English

AGMATINE [MI]

Common Name

English

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Classification Tree

Code System

Code

chemical

DSLD

3255 (Number of products:364)

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Code System

Code

Type

Description

WIKIPEDIA

AGMATINE

PRIMARY

CAS

306-60-5

PRIMARY

EVMPD

SUB33512

PRIMARY

SMS_ID

100000127486

PRIMARY

EPA CompTox

DTXSID0040961

PRIMARY

Showing 1 to 5 of 14 entries

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SUBSTANCE RECORD


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AGMATINE