U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C10H13N5O5
Molecular Weight 283.2407
Optical Activity UNSPECIFIED
Defined Stereocenters 4 / 4
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ISOGUANOSINE

SMILES

NC1=C2N=CN([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C2=NC(=O)N1

InChI

InChIKey=MIKUYHXYGGJMLM-UUOKFMHZSA-N
InChI=1S/C10H13N5O5/c11-7-4-8(14-10(19)13-7)15(2-12-4)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5-,6-,9-/m1/s1

HIDE SMILES / InChI

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
94.0 nM [Ki]
330.0 nM [Ki]
PubMed

PubMed

TitleDatePubMed
Crotonoside exhibits selective post-inhibition effect in AML cells via inhibition of FLT3 and HDAC3/6.
2017 Nov 28
Name Type Language
ISOGUANOSINE
Common Name English
ISOGUANINE RIBOSIDE
Common Name English
NSC-12161
Code English
2,3-DIHYDRO-2-OXOADENOSINE
Systematic Name English
2-HYDROXYADENOSINE
Common Name English
ADENOSINE, 1,2-DIHYDRO-2-OXO-
Systematic Name English
9H-PURIN-2-OL, 6-AMINO-9-.BETA.-D-RIBOFURANOSYL-(6C
Systematic Name English
ADENOSINE, 2,3-DIHYDRO-2-OXO-
Common Name English
Code System Code Type Description
EPA CompTox
DTXSID70939474
Created by admin on Sat Dec 16 12:58:42 GMT 2023 , Edited by admin on Sat Dec 16 12:58:42 GMT 2023
PRIMARY
FDA UNII
6V7FTE1Z1V
Created by admin on Sat Dec 16 12:58:42 GMT 2023 , Edited by admin on Sat Dec 16 12:58:42 GMT 2023
PRIMARY
PUBCHEM
65085
Created by admin on Sat Dec 16 12:58:42 GMT 2023 , Edited by admin on Sat Dec 16 12:58:42 GMT 2023
PRIMARY
CAS
1818-71-9
Created by admin on Sat Dec 16 12:58:42 GMT 2023 , Edited by admin on Sat Dec 16 12:58:42 GMT 2023
PRIMARY
NSC
12161
Created by admin on Sat Dec 16 12:58:42 GMT 2023 , Edited by admin on Sat Dec 16 12:58:42 GMT 2023
PRIMARY