FD&C YELLOW NO. 5 FREE ACID

First approved in 1980

Details

Stereochemistry	ACHIRAL
Molecular Formula	C16H12N4O9S2
Molecular Weight	468.418
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure of FD&C YELLOW NO. 5 FREE ACID

Structure Search

SMILES

OC(=O)C1=NN(C(O)=C1\N=N\C2=CC=C(C=C2)S(O)(=O)=O)C3=CC=C(C=C3)S(O)(=O)=O

InChI

InChIKey=KPIQXPLWZCDIHI-ISLYRVAYSA-N

InChI=1S/C16H12N4O9S2/c21-15-13(18-17-9-1-5-11(6-2-9)30(24,25)26)14(16(22)23)19-20(15)10-3-7-12(8-4-10)31(27,28)29/h1-8,21H,(H,22,23)(H,24,25,26)(H,27,28,29)/b18-17+

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/30305202 | https://www.ncbi.nlm.nih.gov/pubmed/25393426 | https://www.ncbi.nlm.nih.gov/pubmed/24755184

FD&C Yellow No. 5 (Tartrazine, Colour Index No. 19140) is a color additive permitted in the United States for coloring foods (including dietary supplements), ingested and externally applied drugs, and cosmetics. It is a nitrous derivative and is known to cause allergic reactions such as asthma and urticaria, as well as having been the focus of studies on mutagenesis and carcinogenesis due to its transformation into aromatic amine sulfanilic acid after being metabolized by the gastrointestinal microflora.

Approval Year

Name

Type

Language

FD&C YELLOW NO. 5 FREE ACID

Common Name

English

C.I. ACID YELLOW 23 (FREE ACID)

Common Name

English

1H-PYRAZOLE-3-CARBOXYLIC ACID, 4,5-DIHYDRO-5-OXO-1-(4-SULFOPHENYL)-4-(2-(4-SULFOPHENYL)DIAZENYL)-

Systematic Name

English

ACID YELLOW 23 FREE ACID

Common Name

English

5-HYDROXY-1-(4-SULFOPHENYL)-4-(4-SULFOPHENYLAZO)PYRAZOLE-3-CARBOXYLIC ACID

Systematic Name

English

Code System Code Type Description

EPA CompTox

DTXSID8047212