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Details

Stereochemistry ABSOLUTE
Molecular Formula 2C21H25NO4.3H3O4P
Molecular Weight 1004.8405
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of GLAUCINE PHOSPHATE

SMILES

OP(O)(O)=O.OP(O)(O)=O.OP(O)(O)=O.[H][C@]12CC3=CC(OC)=C(OC)C=C3C4=C1C(CCN2C)=CC(OC)=C4OC.[H][C@]56CC7=CC(OC)=C(OC)C=C7C8=C5C(CCN6C)=CC(OC)=C8OC

InChI

InChIKey=NYXQUFHQGCFSDH-UXIZDUDRSA-N
InChI=1S/2C21H25NO4.3H3O4P/c2*1-22-7-6-12-9-18(25-4)21(26-5)20-14-11-17(24-3)16(23-2)10-13(14)8-15(22)19(12)20;3*1-5(2,3)4/h2*9-11,15H,6-8H2,1-5H3;3*(H3,1,2,3,4)/t2*15-;;;/m00.../s1

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Objective evaluation of dextromethorphan and glaucine as antitussive agents.
1984 May
Central action of glaucine in rodents.
1994
Antipoliovirus structure-activity relationships of some aporphine alkaloids.
1998 Apr
Seasonal variation of the chemical constituents from Croton species.
2001 May-Jun
Geographic distribution of three alkaloid chemotypes of Croton lechleri.
2002 Jun
Effects of some antioxidative aporphine derivatives on striatal dopaminergic transmission and on MPTP-induced striatal dopamine depletion in B6CBA mice.
2003 Feb
Alkaloids from Cassytha filiformis and related aporphines: antitrypanosomal activity, cytotoxicity, and interaction with DNA and topoisomerases.
2004 May
Photochemistry of phytoalexins containing phenalenone-like chromophores: photophysics and singlet oxygen photosensitizing properties of the plant oxoaporphine alkaloid oxoglaucine.
2005 Jan-Feb
Structure-affinity relationships of halogenated predicentrine and glaucine derivatives at D1 and D2 dopaminergic receptors: halogenation and D1 receptor selectivity.
2005 Jun 1
Antihyperglycemic effect of aporphines and their derivatives in normal and diabetic rats.
2006 Oct
Cinnamoyl- and hydroxycinnamoyl amides of glaucine and their antioxidative and antiviral activities.
2008 Aug 1
The antinociceptive and anti-inflammatory activities of caulerpin, a bisindole alkaloid isolated from seaweeds of the genus Caulerpa.
2009 Nov 26
Patents

Patents

Name Type Language
GLAUCINE PHOSPHATE
Common Name English
4H-Dibenzo[de,g]quinoline, 5,6,6a,7-tetrahydro-1,2,9,10-tetramethoxy-6-methyl-, (S)-, phosphate (2:3)
Systematic Name English
Code System Code Type Description
FDA UNII
6SVU59BSY2
Created by admin on Sat Dec 16 20:06:48 GMT 2023 , Edited by admin on Sat Dec 16 20:06:48 GMT 2023
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CAS
76849-40-6
Created by admin on Sat Dec 16 20:06:48 GMT 2023 , Edited by admin on Sat Dec 16 20:06:48 GMT 2023
PRIMARY