PSEUDOPELLETIERINE HYDROCHLORIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C9H15NO.ClH
Molecular Weight	189.682
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of PSEUDOPELLETIERINE HYDROCHLORIDE

Structure Search

SMILES

Cl.CN1[C@H]2CCC[C@@H]1CC(=O)C2

InChI

InChIKey=CVGRGXQEVKWHHS-KVZVIFLMSA-N

InChI=1S/C9H15NO.ClH/c1-10-7-3-2-4-8(10)6-9(11)5-7;/h7-8H,2-6H2,1H3;1H/t7-,8+;

HIDE SMILES / InChI

Description
Sources: https://www.creative-enzymes.com/product/pseudopelletierine_8782.html | http://rhodiolarosea.org/pomegranate.pdf

Pseudopelletierine is the main alkaloid derived from the root-bark of the pomegranate tree (Punica granatum). Pseudopelletierine is used as an enzyme substrate.

Originator

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
amyloid beta-protein (1-40) 3 Target ID: amyloid beta-protein (1-40) Sources: https://www.ncbi.nlm.nih.gov/pubmed/19715547	Binding Agent 1064

Conditions

Condition	Modality	Targets	Highest Phase	Product
Alzheimer’s disease 272 Sources: https://www.ncbi.nlm.nih.gov/pubmed/19715547	Primary		Basic research	Unknown Approved Use Unknown

PubMed

Title	Date	PubMed
Dolasetron overdose resulting in prolonged QTc interval and severe hypotension: a case report and literature review.	2007 Jul	17582056
Association constants of pyridine and piperidine alkaloids to amyloid beta peptide determined by electrochemical impedance spectroscopy.	2010 Mar	19715547

Patents

Sample Use Guides

In Vivo Use Guide

Guinea pig: LDLo - subcutaneous, 230 mg/kg

Route of Administration: Other

In Vitro Use Guide

Binding to Abeta(1-40) of pseudopelletierine was (0.57 x 10(8) M(-1)

Name

Type

Language

PSEUDOPELLETIERINE HYDROCHLORIDE

Common Name

English

9-AZABICYCLO(3.3.1)NONAN-3-ONE, 9-METHYL-, HYDROCHLORIDE (1:1)

Systematic Name

English

PSEUDOPELLETIERINE HYDROCHLORIDE [MI]

Common Name

English

NSC-62515

Code

English

9-METHYL-9-AZABICYCLO(3.3.1)NONAN-3-ONE HYDROCHLORIDE

Systematic Name

English

Code System Code Type Description

PUBCHEM

6419951