U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C8H6O4
Molecular Weight 166.1308
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PHTHALIC ACID

SMILES

OC(=O)C1=C(C=CC=C1)C(O)=O

InChI

InChIKey=XNGIFLGASWRNHJ-UHFFFAOYSA-N
InChI=1S/C8H6O4/c9-7(10)5-3-1-2-4-6(5)8(11)12/h1-4H,(H,9,10)(H,11,12)

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
[Effect of dibutyl phthalate on demodicidosis].
2001
Effect of phthalates on the stability and performance of AgBF4-PVP membranes for olefin/paraffin separation.
2001 Oct 21
Phthalates in underground waters of the Zagreb area.
2002 Aug
Retention of ionizable compounds on HPLC. 12. The properties of liquid chromatography buffers in acetonitrile-water mobile phases that influence HPLC retention.
2002 Aug 1
Characterization of the structures of poly(urea-urethane) microcapsules.
2002 Aug 21
In vitro effects of monophthalates on cytokine expression in the monocytic cell line THP-1 and in peripheral blood mononuclear cells from allergic and non-allergic donors.
2002 Dec
A butyrylcholinesterase in the early development of the brine shrimp (Artemia salina) larvae: a target for phthalate ester embryotoxicity?
2002 Dec 13
Gene expression changes induced in mouse liver by di(2-ethylhexyl) phthalate.
2002 Dec 15
Biochemical and structural changes in RBCs stored with different plasticizers: the role of hexanol.
2002 Jul
Slow-stir water solubility measurements of selected alcohols and diesters.
2002 Jul
Structural characterisation of humic acid-bound PAH residues in soil by 13C-CPMAS-NMR-spectroscopy: evidence of covalent bonds.
2002 Jul
Determination of adipate plasticizers in poly(vinyl chloride) by microwave-assisted extraction.
2002 Jul 19
The peroxisome proliferator-activated receptor alpha (PPARalpha): role in hepatocarcinogenesis.
2002 Jul 31
Cytocompatibility of new phthalate ester-free tissue conditioners in vitro.
2002 Jun
Adjuvant effect of di-n-butyl-, di-n-octyl-, di-iso-nonyl- and di-iso-decyl phthalate in a subcutaneous injection model using BALB/c mice.
2002 Nov
Ultrasound-assisted method for determination of chemical oxygen demand.
2002 Nov
Analytical potential of the reaction between p-phenylenediamines and peroxodisulfate for kinetic spectrophotometric determination of traces of ascorbic acid.
2002 Nov
Inhibition of oocyte development in Japanese medaka (Oryzias latipes) exposed to di-2-ethylhexyl phthalate.
2002 Nov
A novel class of self-sufficient cytochrome P450 monooxygenases in prokaryotes.
2002 Nov
Simultaneous determination of phthalate di- and monoesters in poly(vinylchloride) products and human saliva by gas chromatography-mass spectrometry.
2002 Nov 15
Toxicity study of diethyl phthalate on freshwater fish Cirrhina mrigala.
2002 Oct
Reproductive and neurobehavioural toxicity study of bis(2-ethylhexyl) phthalate (DEHP) administered to mice in the diet.
2002 Oct
Defining the cellular and molecular mechanisms of toxicant action in the testis.
2002 Oct 5
Phthalates suppress the calcium signaling of nicotinic acetylcholine receptors in bovine adrenal chromaffin cells.
2002 Sep 1
Source reconciliation of atmospheric gas-phase and particle-phase pollutants during a severe photochemical smog episode.
2002 Sep 1
Phthalates and nonylphenols in profiles of differently dressed soils.
2002 Sep 16
The phthalate diesters DEHP and DBP do not induce lauric acid hydroxylase activity in rainbow trout.
2002 Sep-Dec
Environmental estrogens interact with and modulate the properties of plasma sex steroid-binding proteins in juvenile Atlantic salmon (Salmo salar).
2002 Sep-Dec
Absorption, disposition and metabolism of di-isononyl phthalate (DINP) in F-344 rats.
2002 Sep-Oct
Identification and fragmentation study of plasticizers with post-source decay matrix-assisted laser desorption/ionization mass spectrometry.
2003
Hap4p overexpression in glucose-grown Saccharomyces cerevisiae induces cells to enter a novel metabolic state.
2003
Lack of sensitization for trimellitate, phthalate, terephthalate and isobutyrate plasticizers in a human repeated insult patch test.
2003 Apr
Swelling and drug release behavior of tablets coated with aqueous hydroxypropyl methylcellulose phthalate (HPMCP) nanoparticles.
2003 Apr 29
Degradation of phenanthrene and naphthalene by a Burkholderia species strain.
2003 Feb
Mono- and diesters from o-phthalic acid in leachates from different European landfills.
2003 Feb
Crystal structure of the 1:2:2 adduct of piperazine, o-phthalic acid and water.
2003 Feb
Air quality model evaluation data for organics. 6. C3-C24 organic acids.
2003 Feb 1
Development and application of a generalized physiologically based pharmacokinetic model for multiple environmental contaminants.
2003 Jan
On-line clean-up by multidimensional liquid chromatography-electrospray ionization tandem mass spectrometry for high throughput quantification of primary and secondary phthalate metabolites in human urine.
2003 Jan 25
Quantitative changes in gene expression in fetal rat testes following exposure to di(n-butyl) phthalate.
2003 Jun
Improved quantitative detection of 11 urinary phthalate metabolites in humans using liquid chromatography-atmospheric pressure chemical ionization tandem mass spectrometry.
2003 Jun 15
An estimation of the daily intake of di(2-ethylhexyl)phthalate (DEHP) and other phthalates in the general population.
2003 Mar
Determination of low molecular weight organic acids in soil, plants, and water by capillary zone electrophoresis.
2003 Mar
Phthalate catabolic gene cluster is linked to the angular dioxygenase gene in Terrabacter sp. strain DBF63.
2003 Mar
Removal of bis(2-ethylhexyl) phthalate at a sewage treatment plant.
2003 Mar
Investigation of the adjuvant and immuno-suppressive effects of benzyl butyl phthalate, phthalic acid and benzyl alcohol in a murine injection model.
2003 Mar
Evaluation of the toxicity of polyvinylacetate phthalate in experimental animals.
2003 Mar
Development and optimization of a method for the analysis of low-molecular-mass organic acids in plants by capillary electrophoresis with indirect UV detection.
2003 Mar 14
Transdermal iontophoresis of insulin. II. Physicochemical considerations.
2003 Mar 26
Determination of three phthalate metabolites in human urine using on-line solid-phase extraction-liquid chromatography-tandem mass spectrometry.
2003 May 25
Patents
Name Type Language
PHTHALIC ACID
HSDB   MI   USP-RS  
Systematic Name English
FLUORESCEIN SODIUM IMPURITY B [EP IMPURITY]
Common Name English
NSC-5348
Code English
PHTHALIC ACID [MI]
Common Name English
FLUORESCEIN IMPURITY B [EP IMPURITY]
Common Name English
PHTHALIC ACID [USP IMPURITY]
Common Name English
PHTHALIC ACID [USP-RS]
Common Name English
BENZENE-1,2-DICARBOXYLIC ACID
Systematic Name English
PHTHALIC ACID [HSDB]
Common Name English
O-PHTHALIC ACID
Common Name English
Code System Code Type Description
EPA CompTox
DTXSID8021484
Created by admin on Fri Dec 15 17:45:59 GMT 2023 , Edited by admin on Fri Dec 15 17:45:59 GMT 2023
PRIMARY
ECHA (EC/EINECS)
201-873-2
Created by admin on Fri Dec 15 17:45:59 GMT 2023 , Edited by admin on Fri Dec 15 17:45:59 GMT 2023
PRIMARY
MERCK INDEX
m8753
Created by admin on Fri Dec 15 17:45:59 GMT 2023 , Edited by admin on Fri Dec 15 17:45:59 GMT 2023
PRIMARY Merck Index
DRUG BANK
DB02746
Created by admin on Fri Dec 15 17:45:59 GMT 2023 , Edited by admin on Fri Dec 15 17:45:59 GMT 2023
PRIMARY
PUBCHEM
1017
Created by admin on Fri Dec 15 17:45:59 GMT 2023 , Edited by admin on Fri Dec 15 17:45:59 GMT 2023
PRIMARY
NSC
5348
Created by admin on Fri Dec 15 17:45:59 GMT 2023 , Edited by admin on Fri Dec 15 17:45:59 GMT 2023
PRIMARY
CAS
88-99-3
Created by admin on Fri Dec 15 17:45:59 GMT 2023 , Edited by admin on Fri Dec 15 17:45:59 GMT 2023
PRIMARY
FDA UNII
6O7F7IX66E
Created by admin on Fri Dec 15 17:45:59 GMT 2023 , Edited by admin on Fri Dec 15 17:45:59 GMT 2023
PRIMARY
CHEBI
29069
Created by admin on Fri Dec 15 17:45:59 GMT 2023 , Edited by admin on Fri Dec 15 17:45:59 GMT 2023
PRIMARY
WIKIPEDIA
PHTHALIC ACID
Created by admin on Fri Dec 15 17:45:59 GMT 2023 , Edited by admin on Fri Dec 15 17:45:59 GMT 2023
PRIMARY
RS_ITEM_NUM
1535899
Created by admin on Fri Dec 15 17:45:59 GMT 2023 , Edited by admin on Fri Dec 15 17:45:59 GMT 2023
PRIMARY
HSDB
1339
Created by admin on Fri Dec 15 17:45:59 GMT 2023 , Edited by admin on Fri Dec 15 17:45:59 GMT 2023
PRIMARY
MESH
C032279
Created by admin on Fri Dec 15 17:45:59 GMT 2023 , Edited by admin on Fri Dec 15 17:45:59 GMT 2023
PRIMARY