Fluocortin butyl, a corticosteroid, is available in Germany for nasal application to improve symptoms and signs of perennial rhinitis. This drug is also used in Italy under the brand name Vaspit for the treatment of skin diseases such as dermatitis, eczema, erythema, first-degree burns, and insect bites. Once the cellular environment is reached, the fluocortin butyl induces the expression of protein lipocortin 1, an inhibitor of the enzyme phospholipase A2, an initiator of a cascade of molecular events that leads to the formation of inflammatory mediators such as prostaglandins, and prostacyclins.