U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C7H8O5S
Molecular Weight 204.2
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SULFOGAIACOL

SMILES

COC1=CC(=CC=C1O)S(O)(=O)=O

InChI

InChIKey=QDRCGSIKAHSALR-UHFFFAOYSA-N
InChI=1S/C7H8O5S/c1-12-7-4-5(13(9,10)11)2-3-6(7)8/h2-4,8H,1H3,(H,9,10,11)

HIDE SMILES / InChI
Potassium guaiacolsulfonate also known as sulfoguaiacolum is a salt of GUAIACOLSULFONIC ACID, which is used as an expectorant, to relieve symptoms of cough and mucus in the chest due to respiratory infections, asthma, colds, or hay fever. It works by thinning mucus (phlegm) in the lungs, making it less sticky and easier to cough up. This reduces chest congestion by making coughs more productive.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Palliative
Unknown

Approved Use

Unknown
Palliative
Unknown

Approved Use

Unknown
Palliative
Unknown

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Patents

Patents

Sample Use Guides

Take potassium guaiacolsulfonate by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation. Take potassium guaiacolsulfonate with a full glass of water (8 oz/240 mL). Drink plenty of water while taking potassium guaiacolsulfonate. Do not take 2 doses at once.
Route of Administration: Oral
In Vitro Use Guide
Unknown
Name Type Language
SULFOGAIACOL
INN   WHO-DD  
INN  
Official Name English
4-HYDROXY-3-METHOXYBENZENESULFONIC ACID
Systematic Name English
BENZENESULFONIC ACID, 4-HYDROXY-3-METHOXY-
Common Name English
Sulfogaiacol [WHO-DD]
Common Name English
4-GUAIACOLSULFONIC ACID
Systematic Name English
sulfogaiacol [INN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C29767
Created by admin on Sat Dec 16 16:31:40 GMT 2023 , Edited by admin on Sat Dec 16 16:31:40 GMT 2023
Code System Code Type Description
CHEBI
32033
Created by admin on Sat Dec 16 16:31:40 GMT 2023 , Edited by admin on Sat Dec 16 16:31:40 GMT 2023
PRIMARY
CAS
7134-11-4
Created by admin on Sat Dec 16 16:31:40 GMT 2023 , Edited by admin on Sat Dec 16 16:31:40 GMT 2023
PRIMARY
NCI_THESAURUS
C123387
Created by admin on Sat Dec 16 16:31:40 GMT 2023 , Edited by admin on Sat Dec 16 16:31:40 GMT 2023
PRIMARY
FDA UNII
6L00O0WHZR
Created by admin on Sat Dec 16 16:31:40 GMT 2023 , Edited by admin on Sat Dec 16 16:31:40 GMT 2023
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PUBCHEM
4874
Created by admin on Sat Dec 16 16:31:40 GMT 2023 , Edited by admin on Sat Dec 16 16:31:40 GMT 2023
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EVMPD
SUB10740MIG
Created by admin on Sat Dec 16 16:31:40 GMT 2023 , Edited by admin on Sat Dec 16 16:31:40 GMT 2023
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DRUG CENTRAL
3485
Created by admin on Sat Dec 16 16:31:40 GMT 2023 , Edited by admin on Sat Dec 16 16:31:40 GMT 2023
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SMS_ID
100000091538
Created by admin on Sat Dec 16 16:31:40 GMT 2023 , Edited by admin on Sat Dec 16 16:31:40 GMT 2023
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CHEBI
85537
Created by admin on Sat Dec 16 16:31:40 GMT 2023 , Edited by admin on Sat Dec 16 16:31:40 GMT 2023
PRIMARY
EPA CompTox
DTXSID80991669
Created by admin on Sat Dec 16 16:31:40 GMT 2023 , Edited by admin on Sat Dec 16 16:31:40 GMT 2023
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INN
4151
Created by admin on Sat Dec 16 16:31:40 GMT 2023 , Edited by admin on Sat Dec 16 16:31:40 GMT 2023
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ChEMBL
CHEMBL2110990
Created by admin on Sat Dec 16 16:31:40 GMT 2023 , Edited by admin on Sat Dec 16 16:31:40 GMT 2023
PRIMARY
ECHA (EC/EINECS)
230-434-8
Created by admin on Sat Dec 16 16:31:40 GMT 2023 , Edited by admin on Sat Dec 16 16:31:40 GMT 2023
PRIMARY