U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C14H6ClF3NO5.Na
Molecular Weight 383.639
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ACIFLUORFEN-SODIUM

SMILES

[Na+].[O-]C(=O)C1=CC(OC2=CC=C(C=C2Cl)C(F)(F)F)=CC=C1[N+]([O-])=O

InChI

InChIKey=RVULBHWZFCBODE-UHFFFAOYSA-M
InChI=1S/C14H7ClF3NO5.Na/c15-10-5-7(14(16,17)18)1-4-12(10)24-8-2-3-11(19(22)23)9(6-8)13(20)21;/h1-6H,(H,20,21);/q;+1/p-1

HIDE SMILES / InChI

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
Target ID: Protoporphyrinogen IX oxidase
PubMed

PubMed

TitleDatePubMed
Inhibition of mammalian protoporphyrinogen oxidase by acifluorfen.
1994 Dec
Regulation of CYP 2 A 5 induction by porphyrinogenic agents in mouse primary hepatocytes.
1997 Jan
[Collection of Arabidopsis thaliana mutants with altered sensitivity to oxidative stress inductors].
2001 Sep-Oct
Synthesis of haptens and protein conjugates for the development of immunoassays for the insect growth regulator fenoxycarb.
2002 Jan 2
Photochemistry and photoinduced toxicity of acifluorfen, a diphenyl-ether herbicide.
2002 Jan-Feb
Isoflavone, glyphosate, and aminomethylphosphonic acid levels in seeds of glyphosate-treated, glyphosate-resistant soybean.
2003 Jan 1
Impact of Herbicides on Heterodera glycines Susceptible and Resistant Soybean Cultivars.
2003 Mar
Experimental hepatic uroporphyria induced by the diphenyl-ether herbicide fomesafen in male DBA/2 mice.
2003 May 15
Identification of Botrytis cinerea susceptibility loci in Arabidopsis thaliana.
2004 May
Crystal structure of protoporphyrinogen oxidase from Myxococcus xanthus and its complex with the inhibitor acifluorfen.
2006 Dec 15
Is prochloraz a potent synergist across aquatic species? A study on bacteria, daphnia, algae and higher plants.
2006 Jun 30
The occurrence of hormesis in plants and algae.
2006 Oct 17
Impairment of the photosynthetic apparatus by oxidative stress induced by photosensitization reaction of protoporphyrin IX.
2007 Jun
The analysis of the ChlI 1 and ChlI 2 genes using acifluorfen-resistant mutant of Arabidopsis thaliana.
2007 Mar
Trafficking of siderophore transporters in Saccharomyces cerevisiae and intracellular fate of ferrioxamine B conjugates.
2007 Nov
GCN2-dependent phosphorylation of eukaryotic translation initiation factor-2alpha in Arabidopsis.
2008
Molecular interactions of pesticides at the soil-water interface.
2008 Aug 1
A capillary electrophoresis assay for recombinant Bacillus subtilis protoporphyrinogen oxidase.
2008 Dec 15
Application of saturation transfer double difference NMR to elucidate the mechanistic interactions of pesticides with humic acid.
2008 Feb 15
Site-directed mutagenesis and computational study of the Y366 active site in Bacillus subtilis protoporphyrinogen oxidase.
2009 Sep
Structural insight into unique properties of protoporphyrinogen oxidase from Bacillus subtilis.
2010 Apr
Deficiencies in jasmonate-mediated plant defense reveal quantitative variation in Botrytis cinerea pathogenesis.
2010 Apr 15
Enantioselective degradation in sediment and aquatic toxicity to Daphnia magna of the herbicide lactofen enantiomers.
2010 Feb 24
[Determination of biphenyl ether herbicides in water using HPLC with cloud-point extraction].
2010 Jan
Rapid dark repression of 5-aminolevulinic acid synthesis in green barley leaves.
2010 May
Patents
Name Type Language
ACIFLUORFEN-SODIUM
ISO  
Common Name English
SCIFLUORFEN
Brand Name English
SODIUM 3-CARBOXY-4-NITROPHENYL 2-CHLORO-.ALPHA.,.ALPHA.,.ALPHA.-TRIFLUORO-P-TOLYL ETHER
Common Name English
RH-6201
Code English
SODIUM 5-(2-CHLORO-4-TRIFLUOROMETHYLPHENOXY)-2-NITROBENZOATE
Systematic Name English
ACIFLUORFEN-SODIUM [ISO]
Common Name English
BLAZER
Brand Name English
ACIFLUORFEN SODIUM
Common Name English
BENZOIC ACID, 5-(2-CHLORO-4-(TRIFLUOROMETHYL)PHENOXY)-2-NITRO-, SODIUM SALT (1:1)
Systematic Name English
SODIUM ACIFLUORFEN
Common Name English
ACIFLUORFEN SODIUM SALT [MI]
Common Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 114402
Created by admin on Sat Dec 16 10:43:03 GMT 2023 , Edited by admin on Sat Dec 16 10:43:03 GMT 2023
Code System Code Type Description
ECHA (EC/EINECS)
263-560-7
Created by admin on Sat Dec 16 10:43:03 GMT 2023 , Edited by admin on Sat Dec 16 10:43:03 GMT 2023
PRIMARY
DRUG BANK
DBSALT002807
Created by admin on Sat Dec 16 10:43:03 GMT 2023 , Edited by admin on Sat Dec 16 10:43:03 GMT 2023
PRIMARY
HSDB
6551
Created by admin on Sat Dec 16 10:43:03 GMT 2023 , Edited by admin on Sat Dec 16 10:43:03 GMT 2023
PRIMARY
FDA UNII
6H07I1G902
Created by admin on Sat Dec 16 10:43:03 GMT 2023 , Edited by admin on Sat Dec 16 10:43:03 GMT 2023
PRIMARY
CAS
62476-59-9
Created by admin on Sat Dec 16 10:43:03 GMT 2023 , Edited by admin on Sat Dec 16 10:43:03 GMT 2023
PRIMARY
PUBCHEM
44072
Created by admin on Sat Dec 16 10:43:03 GMT 2023 , Edited by admin on Sat Dec 16 10:43:03 GMT 2023
PRIMARY
ALANWOOD
acifluorfen-sodium
Created by admin on Sat Dec 16 10:43:03 GMT 2023 , Edited by admin on Sat Dec 16 10:43:03 GMT 2023
PRIMARY
EPA CompTox
DTXSID7023853
Created by admin on Sat Dec 16 10:43:03 GMT 2023 , Edited by admin on Sat Dec 16 10:43:03 GMT 2023
PRIMARY
CHEBI
73172
Created by admin on Sat Dec 16 10:43:03 GMT 2023 , Edited by admin on Sat Dec 16 10:43:03 GMT 2023
PRIMARY
MERCK INDEX
m1371
Created by admin on Sat Dec 16 10:43:03 GMT 2023 , Edited by admin on Sat Dec 16 10:43:03 GMT 2023
PRIMARY Merck Index