PHENYLTHIOUREA

Details

Stereochemistry	ACHIRAL
Molecular Formula	C7H8N2S
Molecular Weight	152.217
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC(=S)NC1=CC=CC=C1

InChI

InChIKey=FULZLIGZKMKICU-UHFFFAOYSA-N

InChI=1S/C7H8N2S/c8-7(10)9-6-4-2-1-3-5-6/h1-5H,(H3,8,9,10)

HIDE SMILES / InChI

Approval Year

PubMed

Title	Date	PubMed
Soa genotype selectively affects mouse gustatory neural responses to sucrose octaacetate.	2001 Apr 27	11328963
3-Benzamido, ureido and thioureidoimidazo[1,2-a]pyridine derivatives as potential antiviral agents.	2001 Dec	11767086
Shaping of colony elements in Laomedea flexuosa Hinks (Hydrozoa, Thecaphora) includes a temporal and spatial control of skeleton hardening.	2001 Dec	11751253
Phenylthiocarbamide taste testing in patients with pigmentary glaucoma.	2001 Feb	11177007
Taste receptor cells that discriminate between bitter stimuli.	2001 Feb 23	11222863
The genetics of phenylthiocarbamide perception.	2001 Mar-Apr	11293722
N,N-diethyl-N'-benzoylthiourea--a new spectrophotometric reagent for rhenium determination.	2001 May-Jun	11507834
Generating transparent zebrafish: a refined method to improve detection of gene expression during embryonic development.	2001 Nov	14961324
Effects of juvenile hormone and ecdysone on the timing of vitellogenin appearance in hemolymph of queen and worker pupae of Apis mellifera.	2002	15455035
Dissipation of foliar residues of diafenthiuron and its metabolites.	2002 Jun	12012060
Thiourea toxicity in mouse C3H/10T1/2 cells expressing human flavin-dependent monooxygenase 3.	2002 Jun 1	12093470
Hydrolysis of thionopeptides by the aminopeptidase from Aeromonas proteolytica: insight into substrate binding.	2002 Mar 19	11888288
Application of the artificial neural network in quantitative structure-gradient elution retention relationship of phenylthiocarbamyl amino acids derivatives.	2002 May 15	12008137
Taste and pheromone perception in mammals and flies.	2003	12844351
Unique mechanism of action of the thiourea drug isoxyl on Mycobacterium tuberculosis.	2003 Dec 26	14559907
Combined effect of dopamine and MPP+ on membrane permeability in mitochondria and cell viability in PC12 cells.	2003 Jul	12620283
Field efficacy and baseline toxicities of pyriproxifen, acetamiprid, and diafenthiuron against Bemisia tabaci Gennadius (Homoptera: Aleyrodidae) in Burkina Faso (West Africa).	2003 Nov	14649707
Taste sensitivities to PROP and PTC vary independently in mice.	2003 Oct	14627538
Versatile access to benzhydryl-phenylureas through an unexpected rearrangement during microwave-enhanced synthesis of hydantoins.	2003 Oct 2	14507182
Optical physiology and locomotor behaviors of wild-type and nacre zebrafish.	2004	15602880
Synergistic drug combinations against the in vitro replication of Coxsackie B1 virus.	2004 Apr	15026197
Natural selection and molecular evolution in PTC, a bitter-taste receptor gene.	2004 Apr	14997422
Phenylthiocarbamide tasting and family history of depression, revisited: low rates of depression in families of supertasters.	2004 Apr 15	15081630
Phenylthiourea as a weak activator of aryl hydrocarbon receptor inhibiting 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced CYP1A1 transcription in zebrafish embryo.	2004 Jul 1	15183118
Structure-activity relationship of S-benzylisothiourea derivatives to induce spherical cells in Escherichia coli.	2004 Nov	15564663
Development of N-benzamidothioureas as a new generation of thiourea-based receptors for anion recognition and sensing.	2004 Sep 17	15357607
Phenylthiocarbamide perception in patients with schizophrenia and first-degree family members.	2005 Apr	15800154
Degradation of tyrosinase induced by phenylthiourea occurs following Golgi maturation.	2005 Apr	15760341
Genetics of individual differences in bitter taste perception: lessons from the PTC gene.	2005 Apr	15733260
Purification and characterisation of phenoloxidase from amphioxus Branchiostoma belcheri tsingtauense.	2005 Aug	15752652
Associations between phenylthiocarbamide gene polymorphisms and cigarette smoking.	2005 Dec	16298720
1-Hydroxyalkyl-3-phenylthioureas as novel HDL-elevating agents.	2005 Feb 1	15664862
Highly conserved non-coding sequences are associated with vertebrate development.	2005 Jan	15630479
Thermogravimetric studies of benzoylthiourea-modified MCM-41 after adsorption of mercury ions from aqueous solutions.	2005 Jan	15614361
Pseudogenization of a sweet-receptor gene accounts for cats' indifference toward sugar.	2005 Jul	16103917
Genetic analysis of reproduction in the Buryat populations.	2005 Jul	16079578
Genomic organization, expression, and function of bitter taste receptors (T2R) in mouse and rat.	2005 Jul 14	15886333
Inbred mouse strains C57BL/6J and DBA/2J vary in sensitivity to a subset of bitter stimuli.	2005 Jun 20	15967025
1-Benzhydryl-3-phenylurea and 1-benzhydryl-3-phenylthiourea derivatives: new templates among the CB1 cannabinoid receptor inverse agonists.	2005 Nov 17	16279809
Worldwide haplotype diversity and coding sequence variation at human bitter taste receptor loci.	2005 Sep	16086309
Phenylthiocarbamide: a 75-year adventure in genetics and natural selection.	2006 Apr	16636110
Human glioblastoma ADF cells express tyrosinase, L-tyrosine hydroxylase and melanosomes and are sensitive to L-tyrosine and phenylthiourea.	2006 Jun	16447258
The human sweet tooth.	2006 Jun 15	16934118
Regulation of melanin synthesis by selenium-containing carbohydrates.	2006 Mar	16508177
Characterization of phenoloxidase activity in venom from the ectoparasitoid Nasonia vitripennis (Walker) (Hymenoptera: Pteromalidae).	2007 Feb	17054979

Patents

Name

Type

Language

PHENYLTHIOUREA

Systematic Name

English

PHENYLTHIOCARBAMIDE

Common Name

English

1-PHENYL-2-THIOUREA [HSDB]

Common Name

English

1-PHENYL-2-THIOUREA

Systematic Name

English

NSC-5779

Code

English

N-PHENYLTHIOUREA [MI]

Common Name

English

Code System Code Type Description

MERCK INDEX

m8694