U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C22H27ClF2O4S
Molecular Weight 460.962
Optical Activity UNSPECIFIED
Defined Stereocenters 9 / 9
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CLOTICASONE

SMILES

[H][C@@]12C[C@@H](C)[C@](O)(C(=O)SCCl)[C@@]1(C)C[C@H](O)[C@@]3(F)[C@@]2([H])C[C@H](F)C4=CC(=O)C=C[C@]34C

InChI

InChIKey=ANLWAEZHUOEOTI-GQKYHHCASA-N
InChI=1S/C22H27ClF2O4S/c1-11-6-13-14-8-16(24)15-7-12(26)4-5-19(15,2)21(14,25)17(27)9-20(13,3)22(11,29)18(28)30-10-23/h4-5,7,11,13-14,16-17,27,29H,6,8-10H2,1-3H3/t11-,13+,14+,16+,17+,19+,20+,21+,22+/m1/s1

HIDE SMILES / InChI
Cloticasone is a synthetic glucocorticoid corticosteroid, an analog of fluticasone. Cloticasone was discovered by Glaxo in the 1980s and claimed to be useful as an antiinflammation agent.

Approval Year

Name Type Language
CLOTICASONE
INN  
INN  
Official Name English
S-(CHLOROMETHYL) 6.ALPHA.,9-DIFLUORO-11.BETA.,17-DIHYDROXY-16.ALPHA.-METHYL-3-OXOANDROSTA-1,4-DIENE-17.BETA.-CARBOTHIOATE
Common Name English
cloticasone [INN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C521
Created by admin on Sat Dec 16 16:35:39 GMT 2023 , Edited by admin on Sat Dec 16 16:35:39 GMT 2023
Code System Code Type Description
ChEMBL
CHEMBL2106066
Created by admin on Sat Dec 16 16:35:39 GMT 2023 , Edited by admin on Sat Dec 16 16:35:39 GMT 2023
PRIMARY
FDA UNII
6CN32ZUQ4X
Created by admin on Sat Dec 16 16:35:39 GMT 2023 , Edited by admin on Sat Dec 16 16:35:39 GMT 2023
PRIMARY
NCI_THESAURUS
C90951
Created by admin on Sat Dec 16 16:35:39 GMT 2023 , Edited by admin on Sat Dec 16 16:35:39 GMT 2023
PRIMARY
CAS
87556-66-9
Created by admin on Sat Dec 16 16:35:39 GMT 2023 , Edited by admin on Sat Dec 16 16:35:39 GMT 2023
PRIMARY
PUBCHEM
44481798
Created by admin on Sat Dec 16 16:35:39 GMT 2023 , Edited by admin on Sat Dec 16 16:35:39 GMT 2023
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WIKIPEDIA
Cloticasone
Created by admin on Sat Dec 16 16:35:39 GMT 2023 , Edited by admin on Sat Dec 16 16:35:39 GMT 2023
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EVMPD
SUB06774MIG
Created by admin on Sat Dec 16 16:35:39 GMT 2023 , Edited by admin on Sat Dec 16 16:35:39 GMT 2023
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EPA CompTox
DTXSID10236459
Created by admin on Sat Dec 16 16:35:39 GMT 2023 , Edited by admin on Sat Dec 16 16:35:39 GMT 2023
PRIMARY
INN
5504
Created by admin on Sat Dec 16 16:35:39 GMT 2023 , Edited by admin on Sat Dec 16 16:35:39 GMT 2023
PRIMARY
SMS_ID
100000084053
Created by admin on Sat Dec 16 16:35:39 GMT 2023 , Edited by admin on Sat Dec 16 16:35:39 GMT 2023
PRIMARY