Dichlorotetrafluoroethane is used for cryoanalgesia. Dichlorotetrafluoroethane has been used as an anesthetic in dermabrasion. Cryoanalgesia with dichlorotetrafluoroethane is effective and easily utilized by a dermatologist and a nurse assistant or even by a physician on his own, with occasional help from his patient. Dichlorotetrafluoroethane is a common fluorocarbon aerosol propellant. Dichlorotetrafluoroethane exhibits a vasodepressor activity on skeletal muscle vascular bed, which is readily overcome by the hypotension-induced activation of the sympathetic system but which becomes evident when reflex activity is prevented by vagotomy. The inhalation of fluorocarbons caused a depression of myocardial contractility, aortic hypotension a decrease in cardiac output and an increase in pulmonary vascular resistance. In rats, severe electrocardiographic changes including marked bardycardia, atrioventricular heart block of the second degree and complete heart block were registered.