ARILDONE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H29ClO4
Molecular Weight	368.895
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCC(=O)C(CCCCCCOC1=CC=C(OC)C=C1Cl)C(=O)CC

InChI

InChIKey=DIXRMZGIJNJUGL-UHFFFAOYSA-N

InChI=1S/C20H29ClO4/c1-4-18(22)16(19(23)5-2)10-8-6-7-9-13-25-20-12-11-15(24-3)14-17(20)21/h11-12,14,16H,4-10,13H2,1-3H3

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/7159068

Arildone (also known as Win 38020), an antiviral agent that inhibits replication of herpes simplex virus type 2 and is capable to prevent the poliovirus-induced death in mice.

Approval Year

PubMed

Title	Date	PubMed
Prevention of human poliovirus-induced paralysis and death in mice by the novel antiviral agent arildone.	1982-12	7159068
Antiviral activity of arildone on deoxyribonucleic acid and ribonucleic acid viruses.	1980-08	7447405
Preliminary studies of the mode of action of arildone, a novel antiviral agent.	1979-06	224808
Antiviral activity of some beta-diketones. 2. Aryloxy alkyl diketones. In vitro activity against both RNA and DNA viruses.	1977-06	195055

Patents

Name

Type

Language

NSC-222800

Preferred Name

English

ARILDONE

Official Name

English

WIN 38020

Code

English

ARILDONE [MART.]

Common Name

English

arildone [INN]

Common Name

English

4-[6-(2-Chloro-4-methoxyphenoxy)hexyl]-3,5-heptanedione

Systematic Name

English

ARILDONE [USAN]

Common Name

English

WIN-38020

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C281