Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C16H13ClN2O.ClH |
| Molecular Weight | 321.201 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.O[C@@]1(N2CCN=C2C3=CC=CC=C13)C4=CC=C(Cl)C=C4
InChI
InChIKey=NIUFFPYONFMTAH-NTISSMGPSA-N
InChI=1S/C16H13ClN2O.ClH/c17-12-7-5-11(6-8-12)16(20)14-4-2-1-3-13(14)15-18-9-10-19(15)16;/h1-8,20H,9-10H2;1H/t16-;/m0./s1
Mazindol was developed as an appetite suppressant. It exists in a dynamic equilibrium between three isomers (the keto and the R and S–ol forms, respectively) with the R or S–ol being the only relevant forms at physiologic pH. Both S- and R-mazindol supposed to target human serotonin and dopamine transporters. R-mazindol is the biologically relevant enantiomer.
CNS Activity
Approval Year
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92135810
Created by
admin on Sat Dec 16 10:14:13 GMT 2023 , Edited by admin on Sat Dec 16 10:14:13 GMT 2023
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PRIMARY | |||
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69LI1B79OY
Created by
admin on Sat Dec 16 10:14:13 GMT 2023 , Edited by admin on Sat Dec 16 10:14:13 GMT 2023
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PRIMARY |
SUBSTANCE RECORD
