AZANATOR

Details

Stereochemistry	ACHIRAL
Molecular Formula	C18H18N2O
Molecular Weight	278.3483
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN1CCC(CC1)=C2C3=C(OC4=C2C=CC=N4)C=CC=C3

InChI

InChIKey=ALIOEEFZPKWPAV-UHFFFAOYSA-N

InChI=1S/C18H18N2O/c1-20-11-8-13(9-12-20)17-14-5-2-3-7-16(14)21-18-15(17)6-4-10-19-18/h2-7,10H,8-9,11-12H2,1H3

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/193512 | https://www.ncbi.nlm.nih.gov/pubmed/237114

Azanator (previously known as Sch 15280), a bronchodilator and an antihistamine drug that acts via a non-adrenergic mechanism to block both histaminergically and cholinergically mediated responses in the tracheobronchial tree. Besides, the drug inhibits cyclic CMP phosphodiesterase. Azanator can have a therapeutic application in cases of chronic cough and cystic fibrosis in man.

Approval Year

PubMed

Title	Date	PubMed
Effect of SCH 15280, a new bronchodilator, on cyclic 3',5'-nucleotide phosphodiesterase activity and cyclic 3',5'-adenosine monophosphate levels in guinea pig lung.	1977 May 15	193512

Name

Type

Language

AZANATOR

Official Name

English

5H-(1)BENZOPYRANO(2,3-B)PYRIDINE, 5-(1-METHYL-4-PIPERIDINYLIDENE)-, (Z)-2-BUTENEDIOATE

Systematic Name

English

azanator [INN]

Common Name

English

5-(1-METHYL-4-PIPERIDYLIDENE)-5H-(1)BENZOPYRANO(2,3-B)PYRIDINE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C319